How do I find clinical trials in the UK?

Use TrialConnect to search by condition, location, or eligibility. We index over 29,000 UK clinical trials from ClinicalTrials.gov, updated daily. Enter your condition and we show matching trials near you.

Are there paid clinical trials in the UK?

Yes. Healthy volunteers can earn £500–£3,000 for Phase 1 and bioequivalence studies. TrialConnect lists paid research studies at UK research units in London, Leeds, Nottingham, and more.

What conditions have clinical trials available?

TrialConnect covers 41 conditions including breast cancer, lung cancer, diabetes, heart failure, COPD, multiple sclerosis, Parkinson's disease, Crohn's disease, and many more.

Is TrialConnect free?

Yes. TrialConnect is completely free for patients. We are not affiliated with the NHS or NIHR. Data is sourced from ClinicalTrials.gov.

Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

Cancer

Endometrial (Womb) Cancer Clinical Trials in the UK

Find clinical trials for endometrial cancer in the United Kingdom. Explore treatment pathways including immunotherapy and targeted therapy.

Search Trials →Explore Pathway

Understanding Endometrial Cancer

Endometrial cancer affects ~9,700 women per year in the UK and is the most common gynaecological cancer. Incidence is rising, partly due to increasing obesity. Most cases (75-80%) are diagnosed at an early stage with good prognosis. The TCGA molecular classification system (POLE ultra-mutated, MSI-H, copy-number high, copy-number low) guides treatment decisions.

Treatment Advances

Early stage: surgery (hysterectomy ± lymph node removal). Advanced or recurrent: immunotherapy has transformed treatment - dostarlimab + carboplatin is now standard first-line for advanced disease. For MSI-H tumours (~25-30%), immunotherapy alone (pembrolizumab or dostarlimab) can be remarkably effective. Other options include hormonal therapy (progestins) for low-grade tumours, and combinations of immunotherapy with targeted agents like lenvatinib.

Clinical Trial Opportunities

Active UK trials include: novel immunotherapy combinations, antibody-drug conjugates targeting HER2 (for serous carcinoma), PARP inhibitor combinations, and fertility-preserving approaches for young women. The POLE/MSI biomarker-driven approach is opening new precision medicine trials.