How do I find clinical trials in the UK?

Use TrialConnect to search by condition, location, or eligibility. We index over 29,000 UK clinical trials from ClinicalTrials.gov, updated daily. Enter your condition and we show matching trials near you.

Are there paid clinical trials in the UK?

Yes. Healthy volunteers can earn £500–£3,000 for Phase 1 and bioequivalence studies. TrialConnect lists paid research studies at UK research units in London, Leeds, Nottingham, and more.

What conditions have clinical trials available?

TrialConnect covers 41 conditions including breast cancer, lung cancer, diabetes, heart failure, COPD, multiple sclerosis, Parkinson's disease, Crohn's disease, and many more.

Is TrialConnect free?

Yes. TrialConnect is completely free for patients. We are not affiliated with the NHS or NIHR. Data is sourced from ClinicalTrials.gov.

Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

Cancer

Head & Neck Cancer Clinical Trials in the UK

Find clinical trials for head and neck cancer in the United Kingdom. Explore treatment pathways including immunotherapy and targeted radiation.

Search Trials →Explore Pathway

Understanding Head & Neck Cancer

Head and neck cancers affect ~12,000 people per year in the UK. They include cancers of the mouth, throat (pharynx), voice box (larynx), and salivary glands. Most are squamous cell carcinomas. HPV-positive oropharyngeal cancer (throat) is increasing and generally has better outcomes than HPV-negative disease. Treatment can affect speech, swallowing, and appearance, making quality of life a key research focus.

Treatment Approaches

Early stage: surgery or radiotherapy alone. Locally advanced: chemoradiation (cisplatin + radiotherapy) or surgery followed by radiotherapy ± chemotherapy. Recurrent/metastatic: immunotherapy with pembrolizumab (with or without chemotherapy) is now first-line based on KEYNOTE-048. Cetuximab (anti-EGFR) remains an option for patients who cannot have cisplatin.

Clinical Trial Opportunities

Active UK trials include: de-intensification of treatment for HPV-positive disease (fewer side effects), immunotherapy combinations, new radiation techniques (proton therapy), robotic surgery, and quality of life preservation approaches. The NHS has dedicated head and neck cancer multidisciplinary teams at major centres.