How do I find clinical trials in the UK?

Use TrialConnect to search by condition, location, or eligibility. We index over 29,000 UK clinical trials from ClinicalTrials.gov, updated daily. Enter your condition and we show matching trials near you.

Are there paid clinical trials in the UK?

Yes. Healthy volunteers can earn £500–£3,000 for Phase 1 and bioequivalence studies. TrialConnect lists paid research studies at UK research units in London, Leeds, Nottingham, and more.

What conditions have clinical trials available?

TrialConnect covers 41 conditions including breast cancer, lung cancer, diabetes, heart failure, COPD, multiple sclerosis, Parkinson's disease, Crohn's disease, and many more.

Is TrialConnect free?

Yes. TrialConnect is completely free for patients. We are not affiliated with the NHS or NIHR. Data is sourced from ClinicalTrials.gov.

Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

Cancer

Kidney Cancer (Renal Cell Carcinoma) Clinical Trials in the UK

Find clinical trials for kidney cancer in the United Kingdom. Explore treatment pathways including immunotherapy, targeted therapy, and surgery.

Search Trials →Explore Pathway

Understanding Kidney Cancer

Kidney cancer affects ~13,000 people per year in the UK, with renal cell carcinoma (RCC) being the most common type. Clear cell RCC accounts for ~75% of cases. Many kidney cancers are found incidentally during imaging for other reasons. Early-stage disease has excellent outcomes with surgery alone, while advanced kidney cancer has been transformed by immunotherapy and targeted therapy.

Treatment Advances

Early stage: partial or radical nephrectomy (surgery). Advanced/metastatic: first-line treatment now uses immunotherapy combinations - nivolumab + ipilimumab, or pembrolizumab + axitinib, or avelumab + axitinib. Single-agent TKIs (tyrosine kinase inhibitors) like sunitinib or pazopanib are alternatives. Second-line: nivolumab, cabozantinib, lenvatinib + everolimus, or tivozanib (recently approved by NICE).

Clinical Trial Opportunities

Active UK kidney cancer trials: next-generation immunotherapy combinations, bispecific antibodies, ADCs (antibody-drug conjugates), CAR-T cell therapy targeting carbonic anhydrase IX, neoadjuvant immunotherapy (before surgery), and active surveillance strategies. The NHS has specialist kidney cancer centres with dedicated surgical and medical oncology teams.