Skip to main content
UK clinical trials - updated daily from ClinicalTrials.gov
TrialConnect
← Back to Search
ENROLLING BY INVITATIONPhase1

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

Sponsor: USWM CT, LLC

NCT ID: NCT03391778

View on ClinicalTrials.gov ↗

At a glance

What the study gets you
Access to the study treatment being tested
Type of study
Interventional (receives a drug or procedure)
Time in hospital
In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention
ADP adoptive cell therapy (biological)
How long the study runs
Study runs about 168 months (dates as stated)
About the drug or intervention
ADP adoptive cell therapy — biological: No study drug is administered in this study.
Patient visit burden
Not specified by the sponsor
Type of study
Testing a treatment
Ages
Not specified
Who
All
Number of participants
250
Started
2018-04-09
Last checked
2026-02

Plain English Summary

What is this study?

  • • Testing a new treatment for neoplasms
  • • Phase1 - 250 participants
  • • This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion

Who can take part?

  • • Adults
  • • Diagnosed with neoplasms

Where?

  • • London - University College London Hospitals NHS Foundation Trust
  • • Manchester - USWM CT Investigational Site
  • • Sutton - The Royal Marsden NHS Foundation Trust

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion.

More detail

Participants who received a ADP adoptive cell therapy will be enrolled in this non-therapeutic, multi-center, long term follow-up (LTFU) study and will be followed for up to 15 years post-infusion of lentiviral vector-based adoptive cell therapy. Participants will be monitored for safety following last adoptive cell therapy infusion.

Neoplasms

How this trial compares with your answers

Answer 2 more questions to improve match

What we know so far

Condition· Matched your search
Age· Tell us your age for better matching
Gender· Tell us your sex for better matching

Still need:

  • • Tell us your age for better matching
  • • Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

  • Age: Not specified
  • Who can join: All genders

What the study is looking for

  • ✓Participants who have received at least one dose of ADP adoptive cell therapy agent.
  • ✓Participants who have completed ADP sponsored or supported interventional study or have withdrawn from it.
  • ✓Participants who have completed treatment as part of managed access to a GSK adoptive cell therapy.
  • ✓Contraceptive use by men or women should be consistent with local regulations regarding the methods of contraception...
  • ✓The investigator is responsible for review of medical history.

Who cannot take part

  • ✗\- None
See the full criteria
Inclusion Criteria: * Participants who have received at least one dose of ADP adoptive cell therapy agent. * Participants who have completed ADP sponsored or supported interventional study or have withdrawn from it. * Participants who have completed treatment as part of managed access to a GSK adoptive cell therapy. * Contraceptive use by men or women should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies. * The investigator is responsible for review of medical history. * Capable of giving signed informed consent. Exclusion Criteria: \- None

Where Is This Study? (3 UK sites)

University College London Hospitals NHS Foundation Trust

London NW1 2PG, United Kingdom

Hospital R&D contact (matched)

Rajinder Sidhu - Associate Director, Research Governance and Operations

uclh.jro-communications@nhs.net020 3447 9825

USWM CT Investigational Site

Manchester M20 4BX, United Kingdom

The Royal Marsden NHS Foundation Trust

Sutton SM2 5PT, United Kingdom

Hospital R&D contact (matched)

Mark Brandon-Grove

research.development@rmh.nhs.uk020 3186 5416
Data sourced from ClinicalTrials.gov · Last verified: 2026-02