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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Access to the study treatment being tested
Type of study: Interventional (receives a drug or procedure)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Gene-modified (GM) T cell therapy (genetic)
How long the study runs: Study runs about 298 months (dates as stated)
About the drug or intervention: Gene-modified (GM) T cell therapy — genetic: No investigational product will be administered
Patient visit burden: Not specified by the sponsor

Type of study: Testing a treatment
Ages: Not specified
Who: All
Number of participants: 1,541
Started: 2018-07-19
Last checked: 2026-09

Plain English Summary

What is this study?

• Testing a new treatment for neoplasms
• Phase2/Phase3 - 1,541 participants
• This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T-cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study

Who can take part?

• Adults
• Diagnosed with neoplasms

Where?

• Leeds - Local Institution - 10850
• London - Kings College Hospital
• London - UCL Cancer Institute
• Manchester Withington - Christie Hospital Nhs Trust
• +1 more UK sites

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T-cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Participants who received at least one infusion of GM T cells will be asked to enroll in this LTFU protocol upon either premature discontinuation from, or completion of the prior parent treatment protocol.

Neoplasms

How this trial compares with your answers

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What we know so far

Condition· Matched your search

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Still need:

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: Not specified
Who can join: All genders

What the study is looking for

✓Must understand and voluntarily sign an agreement to take part Form/Informed Assent Form prior to any study-related...

Who cannot take part

✗Not Applicable
✗Other protocol-defined inclusion/exclusion criteria apply

See the full criteria

Inclusion Criteria: * Received at least one gene-modified (GM) T-cell infusion in a previous Celgene sponsored, Juno Therapeutics, other affiliates of BMS, or Celgene alliance partner-sponsored trial, and have discontinued, or completed the post-treatment follow-up period in the parent treatment protocol, as applicable. * Must understand and voluntarily sign an Informed Consent Form/Informed Assent Form prior to any study-related assessments/procedures being conducted. Exclusion Criteria: Not Applicable Other protocol-defined inclusion/exclusion criteria apply

Where Is This Study? (5 UK sites)

Local Institution - 10850

Leeds LS9 7TF, United Kingdom

WITHDRAWN

Kings College Hospital

London SE5 9RS, United Kingdom

Recruiting

Site contact (verified)

Reuben BEnjamin, Site 1085102032991248

UCL Cancer Institute

London WC1E 6BT, United Kingdom

Recruiting

Site contact (verified)

Claire Roddie, Site 10501+4402034479911 (0)

Christie Hospital Nhs Trust

Manchester Withington M20 4BX, United Kingdom

Recruiting

Site contact (verified)

Kim Linton, Site 105020161 918 7227

Somers Cancer Research Building

Shirley Southampton SO16 6YD, United Kingdom

Recruiting

Site contact (verified)

Andrew Davies, Site 10500+442380795246 00 00

How to Get in Touch

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

Sponsor contact

CONTACT

855-907-3286 Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Sponsor contact

CONTACT

Data sourced from ClinicalTrials.gov · Last verified: 2026-09