At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- questionnaire (other)
- How long the study runs
- Study runs about 82 months (dates as stated)
- About the drug or intervention
- questionnaire — other: questionnaire
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 10,000
- Started
- 2018-06-22
- Last checked
- 2024-06
Plain English Summary
What is this study?
- • Testing a new treatment for musculoskeletal pain, frailty, disability
- • Clinical study - 10,000 participants
- • Background The progression and associations of central and peripheral musculoskeletal pain, frailty, disability and fracture risks are not well known
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with musculoskeletal pain, frailty, disability
Where?
- • Nottingham - University of Nottingham
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
Background The progression and associations of central and peripheral musculoskeletal pain, frailty, disability and fracture risks are not well known. This study aims to characterise the development and progression of different frailty, pain and disability phenotypes and their individual associations. Methods A prospective cohort of 10000 people aged \> 18 will be recruited from general practice surgeries, secondary care and the general public. Data collection waves will be at baseline,and then annual follow-ups for up to five years. Data will be collected using a questionnaire asking about demographic characteristics, pain severity (0-10 scales), pain distribution (a pain Mannikin), pain quality (the McGill Pain Questionnaire), central pain (the CAP-Knee Scale), fracture risks (a modified version of the FRAX instrument), frailty (the Fried Criteria and the FRAIL scale) and disability (the FRAIL scale). Discussion Participant data will be analysed to determine phenotypic subgroups of frailty, pain and disability. Further to this, the progression of these characteristics and their influences upon health and wellbeing will be quantified.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
What the study is looking for
- ✓\- Ability to give agreement to take part. Aged 18 and over Frailty score of ≥ 0.12 on the eFI Have or are at risk of...
See the full criteria
Where Is This Study? (1 UK site)
University of Nottingham
Nottingham NG5 1PB, United Kingdom
How to Get in Touch
Bonnie Millar
Sponsor contactCONTACT