At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Baricitinib (drug)
- How long the study runs
- Study runs about 147 months (dates as stated)
- About the drug or intervention
- Baricitinib — drug: Administered orally.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 1 Year to 18 Years
- Who
- All
- Number of participants
- 190
- Started
- 2019-04-05
- Last checked
- 2026-10
Plain English Summary
What is this study?
- • Testing a new treatment for juvenile idiopathic arthritis
- • Phase3 - 190 participants
- • The reason for this study is to see if the study drug baricitinib is safe and effective in the treatment of JIA in participants ages 1 to 17
Who can take part?
- • Ages 1 Year to 18 Years
- • Diagnosed with juvenile idiopathic arthritis
Where?
- • Bristol - Bristol Royal Hospital for Children
- • Liverpool - Alder Hey Children's Hospital
- • London - Great Ormond Street Hospital For Children NHS Foundation Trust
- • Oxford - Oxford University Hospitals - Nuffield Orthopaedic Centre
- • +1 more UK sites
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The reason for this study is to see if the study drug baricitinib is safe and effective in the treatment of JIA in participants ages 1 to 17. This study is for participants that have been enrolled in studies I4V-MC-JAHV (NCT03773978) or I4V-MC-JAHU.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 1 Year - 18 Years
- Who can join: All genders
Treatment history
Treatments you must have had:
- ✓ completed a previous study of baricitinib for the treatment of JIA
Treatments you must NOT have had:
- ✗ a permanent discontinuation of baricitinib in the
What the study is looking for
- ✓Participants must have completed a previous study of baricitinib for the treatment of JIA.
Who cannot take part
- ✗Participants must not have had a permanent discontinuation of baricitinib in the prior study.
- ✗Participants must have not developed an allergy to baricitinib.
See the full criteria
Where Is This Study? (5 UK sites)
Bristol Royal Hospital for Children
Bristol BS2 8BJ, United Kingdom
Alder Hey Children's Hospital
Liverpool L14 5AB, United Kingdom
Great Ormond Street Hospital For Children NHS Foundation Trust
London WC1N 3JH, United Kingdom
Oxford University Hospitals - Nuffield Orthopaedic Centre
Oxford OX3 7LD, United Kingdom
Sheffield Children's Hospital
Sheffield S10 2TH, United Kingdom
How to Get in Touch
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
Sponsor contactCONTACT
Physicians interested in becoming principal investigators please contact
Sponsor contactCONTACT