At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Deep Brain Stimulation (DBS) (device)
- How long the study runs
- Study runs about 130 months (dates as stated)
- About the drug or intervention
- Deep Brain Stimulation (DBS) — device: Deep brain stimulation therapy involves the delivery of electrical signals to targeted structures in the brain to modulate neural circuit activity, and has been used successfully for the treatment of various types of movement disorders, including Parkinson's disease (PD), disabling or essential tremor, and dystonia
- Patient visit burden
- Not specified by the sponsor
In plain English
This study, run by Abbott Medical Devices, looks at outcomes over time for people with movement disorders such as Parkinson's disease, essential tremor, tremor and dystonia who receive an Abbott deep brain stimulation (DBS) system. It follows people having a new implant or a replacement of their battery device (called an IPG, or implanted pulse generator).
Who can take part
- You are due to have a new DBS implant or a replacement of your IPG device with an approved Abbott DBS system within 180 days.
- You (or a legally acceptable representative) give written informed consent before any study-related procedure.
Who may not be able to
- You are taking part, or plan to take part, in another research study that could affect this study's results.
- You have health, social or psychological conditions that, in the researcher's opinion, could limit your ability to take part or attend follow-up visits.
- If the study centre is in the United States: your DBS implant is not for Parkinson's disease or disabling tremor.
- If the study centre is in the United States: the planned lead placement is not at or near the STN, GPi or VIM thalamus (specific brain areas targeted in DBS).
What taking part involves
- • Not stated — ask the trial team
Time commitment: Not stated — ask the trial team about how many visits there are, how long the study lasts and what taking part involves.
Plain-English summary (AI-generated) from registry data. Not eligibility advice — only the trial team can confirm whether you can take part. Use the eligibility checker to see how your health profile matches this trial.
- Type of study
- Observing health over time
- Ages
- Not specified
- Who
- All
- Number of participants
- 1,000
- Started
- 2019-11-26
- Last checked
- 2026-01
Plain English Summary
What is this study?
- • Testing a new treatment for movement disorders
- • Clinical study - 1,000 participants
- • The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia
Who can take part?
- • Adults
- • Diagnosed with movement disorders
Where?
- • Liverpool - The Walton Centre
- • Bristol - Southmead Hospita
- • Glasgow - Queen Elizabeth University Hospital
- • London - King's College Hospital
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
More detail
ADROIT is an international, prospective, multicenter, observational, post-market study intended to collect worldwide long-term safety and effectiveness data on subjects implanted with market-released Abbott DBS systems in routine clinical practice. Subjects will be followed for 5 years after the initial programming visit.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: Not specified
- Who can join: All genders
What the study is looking for
- ✓Subject is scheduled for a new implant or IPG device replacement surgery with a market-released Abbott DBS system...
- ✓Subject, or a legally acceptable representative, must provide written agreement to take part prior to any study-related...
Who cannot take part
- ✗Subject is currently enrolled or plans to enroll in an investigational study that may confound the results of this...
- ✗Study center is located in the United States, and indication for DBS implant is not Parkinson's disease or disabling...
See the full criteria
Where Is This Study? (4 UK sites)
The Walton Centre
Liverpool L9 7LJ, United Kingdom
Southmead Hospita
Bristol BS10 5NB, United Kingdom
Queen Elizabeth University Hospital
Glasgow, United Kingdom
King's College Hospital
London SE5 9RS, United Kingdom
How to Get in Touch
Claudia Salazar, PhD
Sponsor contactCONTACT
Shirisha Chiluka
Sponsor contactCONTACT