At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Medial knee arthroplasty (device)
- How long the study runs
- Study runs about 98 months (dates as stated)
- About the drug or intervention
- Medial knee arthroplasty — device: Surgical intervention where the medial portion of the knee is replaced by an artificial metal and polyethylene implant
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 40 Years to 80 Years
- Who
- All
- Number of participants
- 140
- Started
- 2017-11-24
- Last checked
- 2025-07
Plain English Summary
What is this study?
- • Testing a new treatment for unicompartmental knee replacement
- • NA - 140 participants
- • The overall aim of this prospective, randomised, single-blinded, controlled trial is to compare clinical outcomes and accuracy of implant positioning in Mako robotic UKA versus jig-based Oxford UKA with navigation control
Who can take part?
- • Ages 40 Years to 80 Years
- • Diagnosed with unicompartmental knee replacement
Where?
- • London - UCL Hospital NHS Foundation Trust
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The overall aim of this prospective, randomised, single-blinded, controlled trial is to compare clinical outcomes and accuracy of implant positioning in Mako robotic UKA versus jig-based Oxford UKA with navigation control. Patients receiving the Mako robotic UKA (Stryker Ltd) will form the investigation group and those undergoing the jig-based Oxford UKA (Zimmer-Biomet Ltd) with navigation control will form the control group. The primary objective in this study is to compare accuracy of component positioning as assessed by postoperative low radiation dose CT scan between conventional Jig-based Oxford UKA with navigation control and Mako robotic UKA.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 40 Years - 80 Years
- Who can join: All genders
Treatment history
Treatments you must have had:
- ✓ sufficient postoperative mobility to attend follow-up clinics and allow for radiographs to be taken
What the study is looking for
- ✓• Patient has medial unicompartmental knee osteoarthritis requiring primary UKA
- ✓Patient and Surgeon are in agreement that UKA is the most appropriate treatment
- ✓Patient is fit for surgical intervention following review by surgeon and anaesthetist
- ✓Patient is between 40-80 years of age at time of surgery
- ✓Gender: male and female
Who cannot take part
- ✗• Patient is not suitable for primary UKA e.g. multi-compartmental knee osteoarthritis, anterior cruciate ligament...
- ✗Patient is not medically fit for surgical intervention
- ✗Patient requires revision surgery following previously failed correctional osteotomy or ipsilateral UKA
- ✗Patient is immobile or has another neurological condition affecting musculoskeletal function
- ✗Patient is less than 40 years of age or greater than 80 years of age
See the full criteria
Where Is This Study? (1 UK site)
UCL Hospital NHS Foundation Trust
London NW1 2BU, United Kingdom
How to Get in Touch
Jenni Tahmassebi
Sponsor contactCONTACT
