How do I find clinical trials in the UK?

Use TrialConnect to search by condition, location, or eligibility. We index over 29,000 UK clinical trials from ClinicalTrials.gov, updated daily. Enter your condition and we show matching trials near you.

Are there paid clinical trials in the UK?

Yes. Healthy volunteers can earn £500–£3,000 for Phase 1 and bioequivalence studies. TrialConnect lists paid research studies at UK research units in London, Leeds, Nottingham, and more.

What conditions have clinical trials available?

TrialConnect covers 41 conditions including breast cancer, lung cancer, diabetes, heart failure, COPD, multiple sclerosis, Parkinson's disease, Crohn's disease, and many more.

Is TrialConnect free?

Yes. TrialConnect is completely free for patients. We are not affiliated with the NHS or NIHR. Data is sourced from ClinicalTrials.gov.

Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Health checks and monitoring — no treatment given
Type of study: Observational (no treatment given)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Questionnaire (other)
How long the study runs: Study runs about 84 months (dates as stated)
About the drug or intervention: Questionnaire — other: HRQoL questionnaires
Patient visit burden: Not specified by the sponsor

Type of study: Observing health over time
Ages: 18 Years and over
Who: All
Number of participants: 200
Started: 2019-12-19
Last checked: 2026-06

Plain English Summary

What is this study?

• Testing a new treatment for chronic obstructive pulmonary disease
• Clinical study - 200 participants
• To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it

Who can take part?

• Ages 18 Years and over
• Diagnosed with chronic obstructive pulmonary disease

Where?

• London - Guy's and St. Thomas NHS Foundation Trust

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.

More detail

To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.

Chronic Obstructive Pulmonary DiseaseRespiratory FailureNeuromuscular DiseasesVentilatory Failure

How this trial compares with your answers

Answer 2 more questions to improve match

What we know so far

Condition· Matched your search

Age· Tell us your age for better matching

Gender· Tell us your sex for better matching

Still need:

• Tell us your age for better matching
• Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: 18 Years and over
Who can join: All genders

What the study is looking for

✓Diagnosed with chronic respiratory failure receiving any of:
✓Non-invasive ventilation
✓Prolonged mechanical ventilation
✓Mechanical insufflation-exsufflation therapy

Who cannot take part

✗Aged \<18
✗Significant physical or psychiatric co-morbidity that would prevent compliance with trial protocol

See the full criteria

Inclusion Criteria: Diagnosed with chronic respiratory failure receiving any of: * Non-invasive ventilation * Prolonged mechanical ventilation * Mechanical insufflation-exsufflation therapy Exclusion Criteria: * Aged \<18 * Significant physical or psychiatric co-morbidity that would prevent compliance with trial protocol

Where Is This Study? (1 UK site)

Guy's and St. Thomas NHS Foundation Trust

London SE1 7EH, United Kingdom

Recruiting

Site contact (verified)

Neeraj Shahneeraj.shah@gstt.nhs.uk

Gill Arbanegill.arbane@gstt.nhs.uk

How to Get in Touch

Neeraj Shah, MBBS

Sponsor contact

CONTACT

+442071888070 neeraj.shah@gstt.nhs.uk

Patrick Murphy, MBBS

Sponsor contact

CONTACT

+442071888070 patrick.murphy@gstt.nhs.uk

Data sourced from ClinicalTrials.gov · Last verified: 2026-06