At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Observation (other)
- How long the study runs
- Study runs about 201 months (dates as stated)
- About the drug or intervention
- Observation — other: Physiological Measurements Patient reported questionnaire Blood sampling
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years to 90 Years
- Who
- All
- Number of participants
- 9,500
- Started
- 2010-06-17
- Last checked
- 2026-06
Plain English Summary
What is this study?
- • Testing a new treatment for cardiovascular diseases
- • Clinical study - 9,500 participants
- • This project will examine the diagnosis and prognosis of patients with cardiovascular disease in hospital in- and outpatients and compare their characteristics with normal controls from the community
Who can take part?
- • Ages 18 Years to 90 Years
- • Diagnosed with cardiovascular diseases
Where?
- • Leicester - University Hospitals Leicester
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
This project will examine the diagnosis and prognosis of patients with cardiovascular disease in hospital in- and outpatients and compare their characteristics with normal controls from the community. The cardiovascular diseases studied include coronary artery disease, heart failure, heart attacks, valve disease, cardiac surgery, dysrhythmias, aneurysms, embolism, strokes, peripheral vascular disease and hypertension. Current methods for diagnosis and predicting outcome in patients are limited and may lack accuracy. This study will collect clinical details, and blood and urine samples from patients for analysis of proteins, chemicals and genetic biomarkers which will enable an examination of the pathological mechanisms involved in cardiovascular disease. The data will also be used to improve diagnosis and also improve prediction of outcome in patients (future clinical events such as death, further hospitalisation with cardiovascular disease and the effects of any therapy given to the patients). In this way, we can develop accurate ways of assessing a patient's condition and how it could be effectively managed. The study will last for 20 years.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 90 Years
- Who can join: All genders
What the study is looking for
- ✓All outpatients and inpatients with cardiovascular disease, of either gender
- ✓Aged 18-90 years old
- ✓Healthy volunteers
- ✓From the community without cardiovascular or other diseases
Who cannot take part
- ✗Any patient who is unable to give consent
- ✗Any patient with non-cardiovascular other health condition likely to cause death within 6 months
- ✗Patients know to be infected with HIV, Hepatitis B or any other agent posing an infection risk from unfixed material
See the full criteria
Where Is This Study? (1 UK site)
University Hospitals Leicester
Leicester, United Kingdom
Carolyn Maloney
uhl-tr.researchandinnovationadminmailbox@nhs.net0116 258 8351How to Get in Touch
Emma P Beeston
Sponsor contactCONTACT
Tara Maitland
Sponsor contactCONTACT