At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Not specified by the sponsor
- How long the study runs
- Study runs about 109 months (dates as stated)
- About the drug or intervention
- Not specified by the sponsor
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 600
- Started
- 2020-07-15
- Last checked
- 2026-07
Plain English Summary
What is this study?
- • Testing a new treatment for cachexia; cancer
- • Clinical study - 600 participants
- • People with incurable cancer often have complex individual needs, however there are several common themes encountered when considering this group
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with cachexia; cancer
Where?
- • Edinburgh - St Columba's Hospice
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
People with incurable cancer often have complex individual needs, however there are several common themes encountered when considering this group. As cancer progresses there are series of interactions between the tumour and the patient, producing both local and systemic effects. This altered state of illness can have multiple ill effects including weight loss, fatigue, increased symptom burden and reduction in physical function which all contribute to a reduced quality of life. These areas are often studied in isolation, giving an incomplete picture. A detailed, holistic characterisation of this group of people does not exist. A robust characterisation of people with incurable cancer will allow identification and prioritisation of future research and has the potential to inform new therapeutics and provide justification for treatments. This study aims to collect information about symptoms and quality of life, weight loss and body composition, physical activity and the body's immune response to cancer. Participants with incurable cancer will be recruited to the study from oncology and palliative medicine services in the UK. Participants will answer questionnaires about quality of life and symptoms, have bloods taken for inflammatory marker and cytokine analysis and have their body composition measured by a variety of methods.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
What the study is looking for
- ✓Patients with incurable cancer (that has spread cancer (Clinical, histological, cytological or radiological evidence) or...
- ✓Aged 18-years and over
- ✓Written agreement to take part
Who cannot take part
- ✗Any concomitant medical or psychiatric problems which, in the opinion of the investigator, would increase the risk...
- ✗Participants will not be able to take part in bio-impedance analysis if they have a pacemaker or implantable heart...
See the full criteria
Where Is This Study? (1 UK site)
St Columba's Hospice
Edinburgh EH53RW, United Kingdom
How to Get in Touch
Barry JA Laird, MBCHB MD
Sponsor contactCONTACT