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The Next Leap in Cardiac Magnetic Resonance Imaging:Cycling the Field

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Access to the study treatment being tested
Type of study: Interventional (receives a drug or procedure)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Cardiac Magnetic Resonance Imaging (procedure), Fast Field Cycling - Magnetic Resonance Imaging (procedure), Electrocardiogram (procedure), Echocardiogram (procedure)
How long the study runs: Study runs about 83 months (dates as stated)
About the drug or intervention: Cardiac Magnetic Resonance Imaging — procedure: Cardiac Magnetic Resonance Imaging - Cardiac Scan · Fast Field Cycling - Magnetic Resonance Imaging — procedure: Fast Field Cycling - Magnetic Resonance Imaging Cardiac Scan · Electrocardiogram — procedure: Electrocardiogram · Echocardiogram — procedure: Echocardiogram
Patient visit burden: Not specified by the sponsor

Type of study: Testing a treatment
Ages: 20 Years and over
Who: All
Number of participants: 150
Started: 2020-08-01
Last checked: 2026-04

Plain English Summary

What is this study?

• Testing a new treatment for myocardial infarction
• NA - 150 participants
• The main aim of the study is to build and test a cardiac-specific coil purposely assembled in house to suit the FFC-MRI whole-body prototype and to test if it could be used for clinical cardiac scans in human subject populations

Who can take part?

• Ages 20 Years and over
• Diagnosed with myocardial infarction

Where?

• Aberdeen - Cardiovascular Research Facility
• Aberdeen - University of Aberdeen and NHS Grampian

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

The main aim of the study is to build and test a cardiac-specific coil purposely assembled in house to suit the FFC-MRI whole-body prototype and to test if it could be used for clinical cardiac scans in human subject populations.

More detail

Aberdeen scientists are at the forefront of a new type of magnetic resonance imaging (MRI), having built in-house the only two available prototypes of Fast Field-Cycling MRI in the world - and these already have clinical imaging capabilities. Fast Field-Cycling MRI switches rapidly over a range of field strengths (0.2 T to 200 µT), providing a T1 dispersion curve. This information is invisible to fixed-field scanners and uncovers unique knowledge about motion and interaction between component molecules within a tissue (i.e. water/fat/proteins). In this application the investigators wish to use their in-house expertise further to extend the capability of our Fast Field-Cycling MRI to perform cardiac imaging by building the first-ever cardiac Fast Field-Cycling MRI coil and develop cardiac pulse sequences with ECG gating. The investigators will aim to establish the normalcy of T1 dispersion curves for left ventricular myocardium in healthy volunteers, and further on to distinguish the characteristics of post-myocardial infarction scar T1 dispersion curves.

Myocardial Infarction

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What we know so far

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: 20 Years and over
Who can join: All genders

What the study is looking for

✓Participant who is willing and able to give agreement to take part for participation in the study
✓Healthy volunteers willing to give agreement to take part for participation in the study
✓Patients diagnosed with a previous myocardial infarction

Who cannot take part

✗Unwillingness to participate
✗Claustrophobia
✗safety concern to MRI scanning such as implantable heart devices
✗Pregnancy
✗Body habitus that may preclude comfortable positioning of the volunteer in either of the MRI scanners (\>50cm in...

See the full criteria

Inclusion Criteria: * Participant who is willing and able to give informed consent for participation in the study * Healthy volunteers willing to give informed consent for participation in the study * Patients diagnosed with a previous myocardial infarction Exclusion Criteria: * Unwillingness to participate * Claustrophobia * Contraindication to MRI scanning such as implantable cardiac devices * Participants who have had a previous myocardial infarction in the past of which they may not be aware and this is discovered whilst being scanned on the 3T MRI scanner, or who may have any other cardiology condition that they were previously unaware will not be included in the healthy control group, even if they present themselves to us as "healthy" at the time of the study visit * Pregnancy * Body habitus that may preclude comfortable positioning of the volunteer in either of the MRI scanners (\>50cm in diameter) * Participants with abnormal kidney function that will preclude them from receiving a contrast agent

Where Is This Study? (2 UK sites)

Cardiovascular Research Facility

Aberdeen AB25 2ZD, United Kingdom

Recruiting

Site contact (verified)

Amelia Rudd, MSc01224559473 a.e.rudd@abdn.ac.uk

James Ross, PhD01224437832 james.ross@abdn.ac.uk

University of Aberdeen and NHS Grampian

Aberdeen AB25 2ZD, United Kingdom

Recruiting

Site contact (verified)

Stacey Dawson07890095869 stacey.dawson@abdn.ac.uk

How to Get in Touch

James Ross, PhD

Sponsor contact

CONTACT

01224437832 james.ross@abdn.ac.uk

Amelia Rudd, MSc

Sponsor contact

CONTACT

01224559473 a.e.rudd@abdn.ac.uk

Data sourced from ClinicalTrials.gov · Last verified: 2026-04