At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Observation only (other)
- How long the study runs
- Study runs about 103 months (dates as stated)
- About the drug or intervention
- Observation only — other: Observation only
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 16 Years and over
- Who
- All
- Number of participants
- 20,000
- Started
- 2021-08-06
- Last checked
- 2026-10
Plain English Summary
What is this study?
- • Testing a new treatment for myocardial infarction
- • Clinical study - 20,000 participants
- • Despite the year-on-year decrease, coronary artery disease (CAD) still remains one of the leading cause of mortality worldwide
Who can take part?
- • Ages 16 Years and over
- • Diagnosed with myocardial infarction
Where?
- • London - Barts Health NHS Trust
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
Despite the year-on-year decrease, coronary artery disease (CAD) still remains one of the leading cause of mortality worldwide. With advances in technology and our understanding of cardiac disease, we can now treat CAD using minimally invasive interventional techniques. This has revolutionised treatment for and improved the lives of many patients with CAD. Although trials have assessed various therapeutic strategies in various populations, real-world evidence of intervention and medical treatment among patients with CAD is increasingly recognised as an important part of providing safety and efficacy data and improving the care we provide. This data will add to that literature by assessing the characteristics and outcomes of patients with CAD. It will also identify and characterise predictors of outcomes, improve risk stratification and diagnostic evaluation.
More detail
The collection of data to describe the nationwide practice of percutaneous coronary intervention (PCI) in the UK started with the inception of the British Cardiovascular Intervention Society (BCIS) in 1988. From 1988 to 1991 annual surveys of PCI activity were published in the British Heart Journal. Annual reports from 1992 onwards are available for download from the society's website (http://www.bcis.org.uk), and summaries of some of the key data have been published as reports for distribution to participating hospitals and networks. The initial data collection process was essentially a descriptive survey of activity. Over time the process has evolved becoming more sophisticated with electronic methods for data collection developed by the Central Cardiac Audit Database (CCAD) group. The methods were tested in 1996 as a pilot in selected hospitals, and full UK-wide participation in the electronic collection of PCI data was achieved by 2005. The proposed study includes one of the largest coronary interventional and surgical programmes in the UK at Europe's largest cardiac centre (BHC). This has allowed us to accumulate a large number of patients in just over 4 years. All patients undergoing PCI and CABG are included in this study using a clinical database. The database is password-protected and includes demographic, clinical and outcome data. The database includes patients with simple to complex CAD. We will use this database to test several hypothesis including but not limited to investigating characteristics of patients treated, complications of interventional treatment and outcomes of patients. This research will add substantially to the literature by providing real-world data from a leading coronary centre.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 16 Years and over
- Who can join: All genders
What the study is looking for
- ✓agreement to take part will not be sought for, as patients are automatically included onto a database that we will use for...
- ✓No children will be included in this study.
- ✓Vulnerable adults or those unable to give consent will be included in the study as well if they are referred to the...
- ✓Both male and female patients ≥16 years of age will be included
- ✓All patients will have had an angiogram at BHC.
Who cannot take part
- ✗Patients \<16 years will not be included in this study.
See the full criteria
Where Is This Study? (1 UK site)
Barts Health NHS Trust
London, United Kingdom
How to Get in Touch
Dr. Krishnaraj Rathod
Sponsor contactCONTACT
Dr. Daniel Jones
Sponsor contactCONTACT
