At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- History of being born to hypertensive or normal pregnancy (other)
- How long the study runs
- Study runs about 50 months (dates as stated)
- About the drug or intervention
- History of being born to hypertensive or normal pregnancy — other: CLARITY is an observational study whereby participants will attend one 4-hr visit the Division of Cardiovascular Medicine, University of Oxford at the John Radcliffe Hospital in Oxford, with the option to split the study visit over two days for convenience.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 30 Years to 40 Years
- Who
- All
- Number of participants
- 200
- Started
- 2022-11-17
- Last checked
- 2023-01
Plain English Summary
What is this study?
- • Testing a new treatment for young adult
- • Clinical study - 200 participants
- • The purpose of this study is to understand more about why young people who were born to a hypertensive pregnancy may have increased risk of high blood pressure and are often at increased risk of heart and blood vessel disease later in life
Who can take part?
- • Ages 30 Years to 40 Years
- • Diagnosed with young adult
Where?
- • Oxford - University of Oxford
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The purpose of this study is to understand more about why young people who were born to a hypertensive pregnancy may have increased risk of high blood pressure and are often at increased risk of heart and blood vessel disease later in life.
More detail
Women who develop blood pressure problems during pregnancy are more likely to have high blood pressure (hypertension) in later life as well as heart attacks or strokes. The children born to the pregnancy also tend to have higher blood pressure and are often at increased risk of heart and blood vessel disease later in life. Previous work has shown that children born to pregnancies where the mother has high blood pressure have changes in their blood vessels, heart and brain that can be measured long before they develop high blood pressure or other clinical symptoms. By understanding the pattern of changes cross multiple parts of the body, over a lifetime, the investigators can identify how advanced the underlying disease is for an individual and how their disease is likely to develop over the next few years. The aim of this study is to understand the heart and blood vessel changes of people born to a hypertensive pregnancy once they are in their 20s and 30s. The investigators then hope to use this information to develop new ways to prevent early onset heart and blood vessel disease in these people.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 30 Years - 40 Years
- Who can join: All genders
What the study is looking for
- ✓Participant is willing and able to give agreement to take part for participation in the study
- ✓Male or female, aged 30 to 40 years at time of enrolment
- ✓Participant previously took part in the ALSPAC study
- ✓Able (in the investigator's opinion) and willing to comply with all study requirements
- ✓Adequate understanding of verbal and written English
Who cannot take part
- ✗Pregnant or lactating when they are due to attend for study visit 1
- ✗Less than six months postpartum
- ✗Planning to donate blood within two weeks prior to study visit 1
- ✗Any significant disease or disorder which, in the opinion of the investigator, might influence the participant's...
- ✗Evidence of congenital heart disease or significant chronic disease relevant to cardiovascular or metabolic status
See the full criteria
Where Is This Study? (1 UK site)
University of Oxford
Oxford OX3 9DU, United Kingdom
How to Get in Touch
Katie Suriano
Sponsor contactCONTACT