At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Sample Collection (other)
- How long the study runs
- Study runs about 46 months (dates as stated)
- About the drug or intervention
- Sample Collection — other: Patients will have breath samples collected by blowing into a bag, and sweat samples collected by gauze.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 270
- Started
- 2023-01-30
- Last checked
- 2024-12
Plain English Summary
What is this study?
- • Testing a new treatment for epilepsy
- • Clinical study - 270 participants
- • Breath and sweat samples will be collected from people who have been admitted to hospital after a potential seizure and analysed by the team
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with epilepsy
Where?
- • London - Chalfont Centre for Epilepsy
- • London - National Hospital for Neurology and Neurosurgery
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
Breath and sweat samples will be collected from people who have been admitted to hospital after a potential seizure and analysed by the team. The researchers then hope to identify a pattern of small molecules that can distinguish seizures from other events, and perhaps determine the severity of the seizure.
More detail
Determining whether someone has had an epileptic seizure, or another event, can be challenging and result in the wrong diagnosis. A 'seizure test' used after the event would therefore be very helpful. Researchers have used small molecules released from the body in breath and sweat to detect cancers and other diseases; this study will determine whether a similar method can be used to detect whether someone has had an epileptic seizure.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
What the study is looking for
- ✓Patients who have been admitted to either University College London's Queen's Square EEG-telemetry unit or Chalfont...
- ✓Patients aged 18 years or above
Who cannot take part
- ✗Patients with active infection or who have taken antibiotics within 4 weeks
- ✗Patients on immunosuppressive medications
- ✗Patients with co-morbidities preventing breath collection
- ✗Patients unable to provide agreement to take part.
See the full criteria
Where Is This Study? (2 UK sites)
Chalfont Centre for Epilepsy
London SL9 0RJ, United Kingdom
National Hospital for Neurology and Neurosurgery
London WC1N 3BG, United Kingdom
How to Get in Touch
Eleonora Lugara, PhD
Sponsor contactCONTACT
Grace Luff, MSc
Sponsor contactCONTACT