At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Blood Sample Collection (other)
- How long the study runs
- Study runs about 53 months (dates as stated)
- About the drug or intervention
- Blood Sample Collection — other: Blood for DNA and biomarker analysis
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- Not specified
- Who
- All
- Number of participants
- 1,000
- Started
- 2023-03-01
- Last checked
- 2024-03
Plain English Summary
What is this study?
- • Testing a new treatment for cardiomyopathies
- • Clinical study - 1,000 participants
- • Cardiomyopathies are diseases of the heart muscle
Who can take part?
- • Adults
- • Diagnosed with cardiomyopathies
Where?
- • London - Guys & St Thomas' NHS Foundation Trust
- • London - Kings College Hospital
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
Cardiomyopathies are diseases of the heart muscle. Known genetic factors may account for some cardiomyopathy cases but there is still much to understand about the genetic and environmental causes and how the disease progresses. Finding new ways to diagnose and treat cardiomyopathies could improve the health and well-being of patients with these conditions. This study will collect data from individuals with cardiomyopathy or related heart muscle disease, or with a possible genetic predisposition to cardiomyopathy, and follow them over time to observe the progress of their heart and health. This study will collect DNA, blood samples, and detailed clinical \& lifestyle information at the start of the study, and data collected during routine healthcare visits over time. * learn what causes cardiomyopathy, and therefore how to treat it * understand why cardiomyopathy progresses differently in different people, to improve the ability to recognise who will benefit from different treatments at different times The investigators will collaborate with other centres internationally to collect a large of group of participants with similar cardiomyopathies, providing power to identify new pathways that cause disease and ways of predicting which participants are at risk of having more severe disease.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: Not specified
- Who can join: All genders
What the study is looking for
- ✓Adults with the capacity to consent Children with parental/guardian consent Male and Female
- ✓Meeting the following criteria:
- ✓Patients with a confirmed diagnosis of cardiomyopathy or related condition
- ✓Patients with a family member with cardiomyopathy, or a related condition
- ✓Patients with a genetic variant that may predispose to cardiomyopathy, or a related condition
Who cannot take part
- ✗Patients without the capacity to provide agreement to take part
See the full criteria
Where Is This Study? (2 UK sites)
Guys & St Thomas' NHS Foundation Trust
London, United Kingdom
Kings College Hospital
London, United Kingdom
How to Get in Touch
Study Coordinator
Sponsor contactCONTACT