At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Not specified by the sponsor
- How long the study runs
- Study runs about 53 months (dates as stated)
- About the drug or intervention
- Not specified by the sponsor
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 100
- Started
- 2023-02-24
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for primary aldosteronism
- • Clinical study - 100 participants
- • The goal of this observational study is to see if there is a cyclical or exaggerated diurnal variation in aldosterone production in people with Primary Aldosteronism
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with primary aldosteronism
Where?
- • London - Queen Mary University of London
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The goal of this observational study is to see if there is a cyclical or exaggerated diurnal variation in aldosterone production in people with Primary Aldosteronism.
More detail
The main questions it aims to answer are: * Can we diagnose more people if we used 24 hour urine measurements? * In those with high amounts of aldosterone in their urine, is there a variable pattern to their aldosterone production? Participants will have a 24 hour urine measurement. They will also have multiple blood tests throughout the day to study the variability in aldosterone secretion.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
Biomarkers mentioned
What the study is looking for
- ✓Patients who have been diagnosed with PA and had previous aldosterone samples \<277 pmol/L, a level which would...
- ✓Patients with aldosterone results done at different times that indicate variability in production.
- ✓Willing to consent and participate in the study.
Who cannot take part
- ✗Inability to withdraw β-adrenoceptor antagonist therapy for 2 weeks.
- ✗People on end of life treatment.
See the full criteria
Where Is This Study? (1 UK site)
Queen Mary University of London
London, United Kingdom
How to Get in Touch
Yun Ni Lee
Sponsor contactCONTACT
Tumi Kaminskas
Sponsor contactCONTACT
