How do I find clinical trials in the UK?

Use TrialConnect to search by condition, location, or eligibility. We index over 29,000 UK clinical trials from ClinicalTrials.gov, updated daily. Enter your condition and we show matching trials near you.

Are there paid clinical trials in the UK?

Yes. Healthy volunteers can earn £500–£3,000 for Phase 1 and bioequivalence studies. TrialConnect lists paid research studies at UK research units in London, Leeds, Nottingham, and more.

What conditions have clinical trials available?

TrialConnect covers 41 conditions including breast cancer, lung cancer, diabetes, heart failure, COPD, multiple sclerosis, Parkinson's disease, Crohn's disease, and many more.

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Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Health checks and monitoring — no treatment given
Type of study: Observational (no treatment given)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Not specified by the sponsor
How long the study runs: Study runs about 66 months (dates as stated)
About the drug or intervention: Not specified by the sponsor
Patient visit burden: Not specified by the sponsor

Type of study: Observing health over time
Ages: 18 Years and over
Who: All
Number of participants: 230
Started: 2024-02-08
Last checked: 2026-06

Plain English Summary

What is this study?

• Testing a new treatment for copd
• Clinical study - 230 participants
• There are over 700,000 UK hospital admissions every year with lung disease symptoms

Who can take part?

• Ages 18 Years and over
• Diagnosed with copd

Where?

• London - Guy's & St Thomas' NHS Foundation Trust

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

There are over 700,000 UK hospital admissions every year with lung disease symptoms. Two of the most common lung diseases contributing to these numbers are asthma and chronic obstructive pulmonary disease (COPD). The immunopathology of these diseases is not fully understood. Matched samples from the respiratory tract and circulation will be used to identify immune patterns throughout the respiratory system to elucidate the immunopathology of airway disease.

More detail

In this observational study, we will be enrolling patients with diagnosed or suspected airways disease who are over 18 years old, as well as age matched healthy volunteers with no significant illness. Participants will be asked if they consent to enter the study, invited at clinically relevant time points (treatment change, disease exacerbation etc.) and to optional bronchoscopy visits. It is expected that participants will be seen yearly with any additional exacerbation/treatment visits also recorded. Research visits will occur at King's College London and the Guys and St Thomas' NHS Foundation Trust (GSTFT), with all bronchoscopy visits occurring within GSTFT 1. Disease specific questionnaires. 2. Lung function tests including spirometry or oscillometry (if not performed previously within 6 months) 3. Sputum collection 4. Nasal sampling including nasosorption, nasal brushing, nasal lavage, or nasopharyngeal swabs 5. Exhaled breath 6. Blood samples (\<6 tablespoons) Optional 7. Bronchoscopy involving a flexible fibreoptic camera passed into the lungs to collect bronchoalveolar lavage, bronchosorption, bronchial brushings and bronchial biopsies. 8. To repeat these procedures at later time - expected once per year or at times of clinically relevant changes

COPDAsthmaAirway Disease

How this trial compares with your answers

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What we know so far

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: 18 Years and over
Who can join: All genders

What the study is looking for

✓Participant is willing and able to give agreement to take part for participation in the study
✓Aged 18 years or above
✓Patient: known or suspected airway disease
✓Healthy volunteer: considered to be in good health with no significant other health condition (immune disorder, cancer etc.)

Who cannot take part

✗Known or suspected current lung tuberculosis, HIV (human immunodeficiency virus), Hepatitis B Virus, Hepatitis...
✗Surgery within the preceding 6 weeks
✗Participants who are pregnant
✗Alcohol or recreational drug abuse
✗Diagnosis of immunodeficiency requiring treatment

See the full criteria

Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study * Aged 18 years or above * Patient: known or suspected airway disease * Healthy volunteer: considered to be in good health with no significant comorbidity (immune disorder, cancer etc.) Exclusion Criteria: * Known or suspected current pulmonary tuberculosis, HIV (human immunodeficiency virus), Hepatitis B Virus, Hepatitis C Virus. * Surgery within the preceding 6 weeks * Participants who are pregnant * History of psychiatric, medical, or surgical disorders that in the opinion of the chief investigator may interfere with sample collection, undergo a bronchoscopy, or may compromise study completion or data collection * Alcohol or recreational drug abuse * Diagnosis of immunodeficiency requiring treatment * Unable to provide written informed consent * Unable to read or write English * Be considered, in the opinion of the investigator, to be an unsuitable candidate for the study

Where Is This Study? (1 UK site)

Guy's & St Thomas' NHS Foundation Trust

London SE1 9RT, United Kingdom

Recruiting

Site contact (verified)

Gill Radcliffe02071888070 gillian.radcliffe@gstt.nhs.uk

How to Get in Touch

Gillian Radcliffe, MRes

Sponsor contact

CONTACT

02071888070 gillian.radcliffe@gstt.nhs.uk

Steven Cass, PhD

Sponsor contact

CONTACT

steven.cass@kcl.ac.uk

Data sourced from ClinicalTrials.gov · Last verified: 2026-06