At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Whole body vibration exercise (other)
- How long the study runs
- Study runs about 34 months (dates as stated)
- About the drug or intervention
- Whole body vibration exercise — other: 6-week supervised whole body vibration exercise programme (training sessions three times per week lasting 10 min) alongside a lifestyle education programme
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years to 65 Years
- Who
- All
- Number of participants
- 168
- Started
- 2025-03-31
- Last checked
- 2025-07
Plain English Summary
What is this study?
- • Testing a new treatment for crohn's disease
- • NA - 168 participants
- • Background: Crohn's disease (CD) is a long-term inflammatory condition of the digestive system
Who can take part?
- • Ages 18 Years to 65 Years
- • Diagnosed with crohn's disease
Where?
- • Hatfield - University of Hertfordshire
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
Background: Crohn's disease (CD) is a long-term inflammatory condition of the digestive system. People with CD often have unpredictable and debilitating symptoms, including abdominal pain, diarrhoea and fatigue. In addition, they require long-term treatment with frequent negative effects and often need surgery and hospitalisations. Therefore, people with CD report a lower health-related quality of life (HRQOL) compared with other people. Doctors are constantly trying to find new treatments to improve HRQOL and control symptoms and whole body vibration exercise could be a potential treatment. Exercise might be a simple, safe, and low-cost intervention for improving HRQOL in people with CD. This is because it has the potential to improve several aspects of physical, mental and social well-being simultaneously. Adults with CD have been shown to be less active than the general population and do not meet the recommended daily physical activity guidelines. One barrier to exercise is lack of time, however whole-body vibration exercise (where you stand and squat on a vibrating plate) can be done over a much shorter duration and at a lower intensity to gain potentially similar or at times greater benefits. More research is needed to understand the effects, both positive and negative of vibration exercise in people with CD. Aim: This study begins to understand whether undertaking a supervised 6-week vibration exercise programme for adults with mild to moderately active Crohn's disease improves HRQoL and other symptoms such as fatigue.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 65 Years
- Who can join: All genders
What the study is looking for
- ✓Aged over 18-65 years old
- ✓Clinical diagnosis of CD for at least 4 weeks before randomization
- ✓Mild to moderate active CD (150-220 CDAI)
- ✓Stable medication for at least 4 weeks before randomization
- ✓Able to provide written consent, complete the study questionnaires and travel to the research centre for study...
Who cannot take part
- ✗Over 65 years old Severe or uncontrolled medical conditions that make it undesirable for the patient to participate
- ✗Coexistent serious autoimmune disease such as rheumatoid arthritis or systemic sclerosis
- ✗Planned major surgery within the first 3 months after randomization
- ✗Are pregnant, or are planning pregnancy within the first 3 months after randomization
- ✗Poor tolerability to venepuncture or lack of adequate venous access for required blood sampling
See the full criteria
Where Is This Study? (1 UK site)
University of Hertfordshire
Hatfield AL10 9EU, United Kingdom
How to Get in Touch
Lindsay Bottoms
Sponsor contactCONTACT