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Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Access to the study treatment being tested
Type of study: Interventional (receives a drug or procedure)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Pyridoxal 5'-Phosphate (100 mg) (supplement), Placebo (other)
How long the study runs: Study runs about 24 months (dates as stated)
About the drug or intervention: Pyridoxal 5'-Phosphate (100 mg) — supplement: 100 mg Pyridoxal 5'-Phosphate tablet once daily with food · Placebo — other: Placebo tablet once daily
Patient visit burden: Not specified by the sponsor

Type of study: Testing a treatment
Ages: 18 Years to 60 Years
Who: All
Number of participants: 40
Started: 2024-11-08
Last checked: 2026-10

Plain English Summary

What is this study?

• Testing a new treatment for autism
• NA - 40 participants
• This clinical trial aims to explore the effect of Vitamin B6 supplementation on anxiety sensory hyperreactivity in autistic adults

Who can take part?

• Ages 18 Years to 60 Years
• Diagnosed with autism

Where?

• Reading - University of Reading

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

This clinical trial aims to explore the effect of Vitamin B6 supplementation on anxiety sensory hyperreactivity in autistic adults. Researchers will compare a placebo group to high-dose Vitamin-B6 to see if vitamin B6 reduce anxiety and sensory reactivity differences in autism.

More detail

The main question it aims to answer is: * Does high-dose Vitamin B6 supplementation reduce sensory hyperreactivity differences in autism? * Does high-dose Vitamin B6 supplementation reduce anxiety differences in autism? * Explore the effects of vitamin B6 on sleep quality, Attention Deficit Hyperactivity Disorder (ADHD) scores, and various visual perception tasks that are indicative of GABAergic activity

Autism

How this trial compares with your answers

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What we know so far

Condition· Matched your search

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Still need:

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: 18 Years - 60 Years
Who can join: All genders

What the study is looking for

✓Between the ages of 18 to 60
✓With a diagnosis of autism

Who cannot take part

✗Taking any supplement that contains more than 2mg of Vitamin B6 or taking GABA agonist drugs
✗Have a medical history of peripheral neuropathy
✗lactose intolerance (placebo tablet is lactose based)

See the full criteria

Inclusion Criteria: * Between the ages of 18 to 60 * With a diagnosis of autism Exclusion Criteria: * Taking any supplement that contains more than 2mg of Vitamin B6 or taking GABA agonist drugs * Have a medical history of peripheral neuropathy * lactose intolerance (placebo tablet is lactose based)

Where Is This Study? (1 UK site)

University of Reading

Reading RG6 6AL, United Kingdom

Recruiting

Site contact (verified)

David Field0118 378 8523 d.t.field@reading.ac.uk

How to Get in Touch

Dr David T Field, PhD

Sponsor contact

CONTACT

+441183785004 d.t.field@reading.ac.uk

Alex Cameron, MSc

Sponsor contact

CONTACT

a.cameron@pgr.reading.ac.uk

Data sourced from ClinicalTrials.gov · Last verified: 2026-10