At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Nerandomilast (drug)
- How long the study runs
- Study runs about 36 months (dates as stated)
- About the drug or intervention
- Nerandomilast — drug: Nerandomilast
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 1,666
- Started
- 2024-05-06
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for idiopathic pulmonary fibrosis
- • Phase3 - 1,666 participants
- • This study is open to people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF)
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with idiopathic pulmonary fibrosis
Where?
- • Aberdeen - Aberdeen Royal Infirmary
- • Birmingham - Queen Elizabeth Hospital Birmingham
- • Bristol - Southmead Hospital
- • Edinburgh - Royal Infirmary of Edinburgh
- • +9 more UK sites
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
This study is open to people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). They can only take part if they have completed treatment in a previous study with a medicine called nerandomilast or BI 1015550. The goal of this study is to find out how well people with pulmonary fibrosis tolerate long- term treatment with nerandomilast. The study also tests whether nerandomilast improves lung function and prolongs the time until symptoms get worse, participants need to go to the hospital, or die. Every participant takes nerandomilast as tablets for up to 1 year and 10 months. The participants may also continue their regular treatment for pulmonary fibrosis during the study. Participants visit their doctors regularly. During these visits, the doctors collect information on any health problems of the participants. Participants also regularly do lung function tests.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
What the study is looking for
- ✓Signed and dated written agreement to take part in accordance with ICH-GCP and local legislation prior to admission to the...
Who cannot take part
- ✗Any disease that may put the patient at risk when participating in this trial at investigator's discretion.
- ✗Patient exhibits suicidality, in the clinical judgment of the investigator or according to the following criteria at...
- ✗any suicidal behaviour (i.e. actual attempt, interrupted attempt, aborted attempt, or preparatory acts or behaviour)
- ✗Patients with clinically relevant severe depression at investigator's discretion or a Hospital Anxiety and...
- ✗An occurrence of malignant tumour other than appropriately treated basal cell carcinoma or in situ squamous cell...
See the full criteria
Where Is This Study? (13 UK sites)
Aberdeen Royal Infirmary
Aberdeen AB25 2ZN, United Kingdom
Queen Elizabeth Hospital Birmingham
Birmingham B15 2GW, United Kingdom
Southmead Hospital
Bristol BS10 5NB, United Kingdom
Royal Infirmary of Edinburgh
Edinburgh EH16 4SA, United Kingdom
Royal Devon and Exeter Hospital, Wonford
Exeter EX2 5DW, United Kingdom
Royal Lancaster Infirmary
Lancaster LA1 4RP, United Kingdom
St James's University Hospital
Leeds LS9 7TF, United Kingdom
Guy's Hospital
London SE1 9RT, United Kingdom
Royal Brompton Hospital
London SW3 6NP, United Kingdom
Altnagelvin Area Hospital
Londonderry BT47 6SB, United Kingdom
Wythenshawe Hospital
Manchester M23 9QZ, United Kingdom
Churchill Hospital
Oxford OX3 7LE, United Kingdom
Southampton General Hospital
Southampton SO16 6YD, United Kingdom
