At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Lung function tests (other)
- How long the study runs
- Study runs about 39 months (dates as stated)
- About the drug or intervention
- Lung function tests — other: Pulmonary function tests
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 2,000
- Started
- 2024-02-27
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for asthma
- • Clinical study - 2,000 participants
- • This study aims to assess the concordance of international asthma guidelines in the diagnosis of asthma and explore the presence of airways disease using additional non-guideline physiologic criteria, such as IOS (impulse osciollometry), not included in the guidelines, but available in the Portsmouth lung function service
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with asthma
Where?
- • Portsmouth - Portsmouth Hospitals University NHS Trust
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
This study aims to assess the concordance of international asthma guidelines in the diagnosis of asthma and explore the presence of airways disease using additional non-guideline physiologic criteria, such as IOS (impulse osciollometry), not included in the guidelines, but available in the Portsmouth lung function service.
More detail
Asthma is a widespread condition that affects millions of people worldwide. It is characterized by symptoms such as difficulty breathing, coughing, and wheezing. Diagnosing asthma involves identifying certain indicators like airflow obstruction, airway sensitivity, and inflammation. However, different international guidelines, including those from organizations such as NICE (National Institute for Health and Care Excellence), GINA (Global Initiative for Asthma), and BTS (British Thoracic Society)/SIGN (Scottish Intercollegiate Guidelines Network), have varying criteria for diagnosis. This can lead to inconsistencies in identifying patients with asthma. This study aims to evaluate the effectiveness of different diagnostic approaches, including impulse oscillometry (IOS), in diagnosing asthma. IOS is a simple and non-invasive test that measures lung function. It has the potential to enhance the accuracy and ease of asthma diagnosis. Despite its promise, current research on the role of IOS in diagnosing asthma in adults is limited. To address these gaps in knowledge, the study will examine the data of patients attending the severe asthma service at Queen Alexandra Hospital in Portsmouth. With an "opt-out" consent process, routine outpatient lung function data will be analysed, paying special attention to the usefulness of IOS compared to other lung function indices in diagnosing asthma. By conducting this study, the aim is to contribute valuable insights to the field of asthma diagnosis. The study findings may help refine the methodology of diagnosing asthma and potentially expand the diagnostic toolkit to include IOS. This could improve the precision and ease of managing asthma, leading to better outcomes for patients.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
What the study is looking for
- ✓The patient will meet all the following criteria to be considered eligible for the study:
- ✓Aged 18 years or over.
- ✓All patients who have attended full asthma workups from November 2021 till date
- ✓Willing and able to consent to use their data in this study (opt-out form or e-consent).
Who cannot take part
- ✗The participant may not enter the study if either of the following apply:
- ✗Unable to comprehend the study and provide agreement to take part, e.g., insufficient command of English in the absence of...
- ✗Patients with other primary respiratory conditions, such as ILD.
See the full criteria
Where Is This Study? (1 UK site)
Portsmouth Hospitals University NHS Trust
Portsmouth, United Kingdom
How to Get in Touch
celia Selvin-Premkumar
Sponsor contactCONTACT