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UNKNOWNPhase1

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Sponsor: Modern Biosciences Ltd

NCT ID: NCT06379958

View on ClinicalTrials.gov ↗

At a glance

What the study gets you
Access to the study treatment being tested
Type of study
Interventional (receives a drug or procedure)
Time in hospital
In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention
leramistat 40mg (drug), Itraconazole 200 mg (drug), Phenytoin 100 Mg Oral Capsule (drug), Simvastatin 40mg (drug)
How long the study runs
Study runs about 5 months (dates as stated)
About the drug or intervention
leramistat 40mg — drug: Oral capsule · Itraconazole 200 mg — drug: Oral capsule · Phenytoin 100 Mg Oral Capsule — drug: Oral capsule · Simvastatin 40mg — drug: Oral capsule · Upadacitinib 15 MG — drug: Oral Capsule
Patient visit burden
Not specified by the sponsor
Type of study
Testing a treatment
Ages
18 Years to 55 Years
Who
All
Number of participants
48
Started
2024-04-08
Last checked
2024-08

Plain English Summary

What is this study?

  • • Testing a new treatment for pharmacokinetics
  • • Phase1 - 48 participants
  • • A DDI study consisting of 4 parts conducted as an open label, fixed sequence study in healthy adult subjects

Who can take part?

  • • Ages 18 Years to 55 Years
  • • Diagnosed with pharmacokinetics

Where?

  • • Belfast - Celerion

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

A DDI study consisting of 4 parts conducted as an open label, fixed sequence study in healthy adult subjects.

Pharmacokinetics

How this trial compares with your answers

Answer 2 more questions to improve match

What we know so far

Condition· Matched your search
Age· Tell us your age for better matching
Gender· Tell us your sex for better matching

Still need:

  • • Tell us your age for better matching
  • • Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

  • Age: 18 Years - 55 Years
  • Who can join: All genders

What the study is looking for

  • ✓Healthy, adult, male or female of non childbearing potential 18 to 55 years of age.
  • ✓Principal

Who cannot take part

  • ✗History or presence of clinically significant medical or psychiatric condition or disease in the opinion of the PI...
  • ✗History of any illness that, in the opinion of the PI or designee, might confound the results of the study or poses...
See the full criteria
Principal Inclusion Criteria: Healthy, adult, male or female of non childbearing potential 18 to 55 years of age. Principal Exclusion Criteria: History or presence of clinically significant medical or psychiatric condition or disease in the opinion of the PI or designee. History of any illness that, in the opinion of the PI or designee, might confound the results of the study or poses an additional risk to the subject by their participation in the study.

Where Is This Study? (1 UK site)

Celerion

Belfast, United Kingdom

Recruiting
Site contact (verified)
Nadine AbdullahPrincipal Investigator

How to Get in Touch

Study Team

Sponsor contact

CONTACT

+44 (0)207 444 0066 ist05@istesso.co.uk
Data sourced from ClinicalTrials.gov · Last verified: 2024-08