At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- leramistat 40mg (drug), Itraconazole 200 mg (drug), Phenytoin 100 Mg Oral Capsule (drug), Simvastatin 40mg (drug)
- How long the study runs
- Study runs about 5 months (dates as stated)
- About the drug or intervention
- leramistat 40mg — drug: Oral capsule · Itraconazole 200 mg — drug: Oral capsule · Phenytoin 100 Mg Oral Capsule — drug: Oral capsule · Simvastatin 40mg — drug: Oral capsule · Upadacitinib 15 MG — drug: Oral Capsule
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years to 55 Years
- Who
- All
- Number of participants
- 48
- Started
- 2024-04-08
- Last checked
- 2024-08
Plain English Summary
What is this study?
- • Testing a new treatment for pharmacokinetics
- • Phase1 - 48 participants
- • A DDI study consisting of 4 parts conducted as an open label, fixed sequence study in healthy adult subjects
Who can take part?
- • Ages 18 Years to 55 Years
- • Diagnosed with pharmacokinetics
Where?
- • Belfast - Celerion
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
A DDI study consisting of 4 parts conducted as an open label, fixed sequence study in healthy adult subjects.
Pharmacokinetics
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Condition· Matched your search
Age· Tell us your age for better matching
Gender· Tell us your sex for better matching
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 55 Years
- Who can join: All genders
What the study is looking for
- ✓Healthy, adult, male or female of non childbearing potential 18 to 55 years of age.
- ✓Principal
Who cannot take part
- ✗History or presence of clinically significant medical or psychiatric condition or disease in the opinion of the PI...
- ✗History of any illness that, in the opinion of the PI or designee, might confound the results of the study or poses...
See the full criteria
Principal Inclusion Criteria:
Healthy, adult, male or female of non childbearing potential 18 to 55 years of age.
Principal Exclusion Criteria:
History or presence of clinically significant medical or psychiatric condition or disease in the opinion of the PI or designee.
History of any illness that, in the opinion of the PI or designee, might confound the results of the study or poses an additional risk to the subject by their participation in the study.
Where Is This Study? (1 UK site)
Celerion
Belfast, United Kingdom
Site contact (verified)
Nadine AbdullahPrincipal Investigator
How to Get in Touch
Study Team
Sponsor contactCONTACT
+44 (0)207 444 0066 ist05@istesso.co.uk
Data sourced from ClinicalTrials.gov · Last verified: 2024-08
