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Use TrialConnect to search by condition, location, or eligibility. We index over 29,000 UK clinical trials from ClinicalTrials.gov, updated daily. Enter your condition and we show matching trials near you.

Are there paid clinical trials in the UK?

Yes. Healthy volunteers can earn £500–£3,000 for Phase 1 and bioequivalence studies. TrialConnect lists paid research studies at UK research units in London, Leeds, Nottingham, and more.

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TrialConnect covers 41 conditions including breast cancer, lung cancer, diabetes, heart failure, COPD, multiple sclerosis, Parkinson's disease, Crohn's disease, and many more.

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Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Health checks and monitoring — no treatment given
Type of study: Observational (no treatment given)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Not specified by the sponsor
How long the study runs: Study runs about 93 months (dates as stated)
About the drug or intervention: Not specified by the sponsor
Patient visit burden: Not specified by the sponsor

Type of study: Observing health over time
Ages: Not specified
Who: All
Number of participants: 424
Started: 2024-10-14
Last checked: 2026-09

Plain English Summary

What is this study?

• Testing a new treatment for primary biliary cholangitis
• Clinical study - 424 participants
• This study will collect information from participants with Primary Biliary Cholangitis (PBC) as they use the drug elafibranor in real world setting

Who can take part?

• Adults
• Diagnosed with primary biliary cholangitis

Where?

• Aberdeen - Aberdeen Royal Infirmary NHS Grampian Grampian Health Board
• Belfast - Belfast Health and Social Care Trust - Royal Victoria Hospital
• Birmingham - Queen Elizabeth Hospital Birmingham - University Hospitals Birmingham NHS Foundation Trust
• Bradford - Bradford Royal Infirmary - Bradford Teaching Hospitals NHS Foundation
• +5 more UK sites

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

This study will collect information from participants with Primary Biliary Cholangitis (PBC) as they use the drug elafibranor in real world setting. PBC is a progressive rare liver disease in which tubes in the liver called bile ducts are damaged. The liver damage in PBC may lead to scarring (cirrhosis). PBC may also be associated with multiple symptoms including pruritus (itching) and fatigue. Many patients with PBC may require liver transplant or may die if the disease progresses and a liver transplant is not done. In this study the main aim is to observe the effectiveness, safety and tolerability of elafibranor in participants with PBC who are receiving treatment in real world setting. The total study duration for each participants will be 60 months (approximately 5 years).

Primary Biliary Cholangitis

How this trial compares with your answers

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What we know so far

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: Not specified
Who can join: All genders

What the study is looking for

✓Participant has provided written agreement to take part and agrees to comply with the study protocol.
✓Participant with PBC diagnosis.
✓Participant for whom the treating physician has decided to start or participants who are currently receiving...
✓If a participant has a caregiver who agrees to complete the caregiver questionnaires, an agreement to take part should be...

Who cannot take part

✗Participant is currently participating or, plans to participate in an investigational drug study or medical device...
✗Participant with known hypersensitivity to the product or to any of its excipients.
✗Participant with mental instability or incompetence, such that the validity of agreement to take part or ability to be...

See the full criteria

Inclusion Criteria: * Participant has provided written informed consent and agrees to comply with the study protocol. * Participant with PBC diagnosis. * Participant for whom the treating physician has decided to start or participants who are currently receiving treatment with commercialized elafibranor. * If a participant has a caregiver who agrees to complete the caregiver questionnaires, an informed consent should be collected from the caregiver before any data is collected. Exclusion Criteria: * Participant is currently participating or, plans to participate in an investigational drug study or medical device study containing active substance. * Participant with known hypersensitivity to the product or to any of its excipients. * Participant with mental instability or incompetence, such that the validity of informed consent or ability to be compliant with the study is uncertain.