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An Observational Study of Predictors and Outcomes of Lung Cancer in Never-smokers in the UK

Sponsor: University College London Hospitals

NCT ID: NCT06575439

View on ClinicalTrials.gov ↗

At a glance

What the study gets you
Health checks and monitoring — no treatment given
Type of study
Observational (no treatment given)
Time in hospital
In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention
Not specified by the sponsor
How long the study runs
Study runs about 60 months (dates as stated)
About the drug or intervention
Not specified by the sponsor
Patient visit burden
Not specified by the sponsor

In plain English

This study looks at lung cancer in people who have never smoked. Researchers want to understand what may predict this cancer and what the outcomes are. The study is run by University College London Hospitals in the UK.

Who can take part

  • Adults aged 18 or over
  • People diagnosed or treated for primary lung cancer at a participating study site, based on scans or tissue tests

Who may not be able to

  • People who have ever smoked — this means more than 100 cigarettes or 75g of tobacco in their lifetime
  • People who have had a prescription for nicotine replacement therapy
  • For new participants, people who cannot give their consent

What taking part involves

  • • Not stated — ask the trial team

Time commitment: Not stated — ask the trial team.

Plain-English summary (AI-generated) from registry data. Not eligibility advice — only the trial team can confirm whether you can take part. Use the eligibility checker to see how your health profile matches this trial.

Type of study
Observing health over time
Ages
18 Years and over
Who
All
Number of participants
225
Started
2024-09-17
Last checked
2024-12

Plain English Summary

What is this study?

  • • Testing a new treatment for lung cancer
  • • Clinical study - 225 participants
  • • The goal of this observational study is to improve the early detection of lung cancer in adults who have smoked less than 100 tobacco cigarettes ("never-smokers") in the United Kingdom

Who can take part?

  • • Ages 18 Years and over
  • • Diagnosed with lung cancer

Where?

  • • London - University College London Hospital

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

The goal of this observational study is to improve the early detection of lung cancer in adults who have smoked less than 100 tobacco cigarettes ("never-smokers") in the United Kingdom. The main questions it aims to answer are: * To describe characteristics such as demographics, co-morbidities and environmental exposures * To describe participant pathways including presentation mode and symptoms to understand if earlier diagnosis would be possible * To describe participant outcomes such as cancer stage, treatment and mortality * To quantitatively or qualitatively measure modifiable and non-modifiable factors that may be associated with LCINS including environmental measures, blood tests and genomic data. Participants will currently have no change to their usual care.

Lung Cancer

How this trial compares with your answers

Answer 2 more questions to improve match

What we know so far

Condition· Matched your search
Age· Tell us your age for better matching
Gender· Tell us your sex for better matching

Still need:

  • • Tell us your age for better matching
  • • Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

  • Age: 18 Years and over
  • Who can join: All genders

What the study is looking for

  • ✓All adult participants from age of 18 who are diagnosed or treated with primary lung cancer through radiology or...

Who cannot take part

  • ✗Participants who have ever smoked cigarettes or tobacco will be excluded; this is defined as:
  • ✗More than 100 cigarettes or 75g tobacco in their lifetime
  • ✗Those who have received a prescription for nicotine replacement therapy
  • ✗For prospective participants, those who cannot consent will be excluded
See the full criteria
Inclusion Criteria: * All adult participants from age of 18 who are diagnosed or treated with primary lung cancer through radiology or histology at any participating study site Exclusion Criteria: * Participants who have ever smoked cigarettes or tobacco will be excluded; this is defined as: * More than 100 cigarettes or 75g tobacco in their lifetime * Those who have received a prescription for nicotine replacement therapy * For prospective participants, those who cannot consent will be excluded

Where Is This Study? (1 UK site)

University College London Hospital

London, United Kingdom

Recruiting
Hospital R&D contact (matched)

Rajinder Sidhu - Associate Director, Research Governance and Operations

uclh.jro-communications@nhs.net020 3447 9825

How to Get in Touch

Neal Navani, PhD

Sponsor contact

CONTACT

020 7679 2000 n.navani@ucl.ac.uk

Sindhu Naidu, MBBS

Sponsor contact

CONTACT

020 7679 2000 s.naidu@ucl.ac.uk
Data sourced from ClinicalTrials.gov · Last verified: 2024-12