At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- BMS-986393 (drug), Cyclophosphamide (drug), Fludarabine (drug), Daratumumab (drug)
- How long the study runs
- Study runs about 87 months (dates as stated)
- About the drug or intervention
- BMS-986393 — drug: Specified dose on specified days · Cyclophosphamide — drug: Specified dose on specified days · Fludarabine — drug: Specified dose on specified days · Daratumumab — drug: Specified dose on specified days · Pomalidomide — drug: Specified dose on specified days · Dexamethasone — drug: Specified dose on specified days · Carfilzomib — drug: Specified dose on specified days
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 440
- Started
- 2025-03-12
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for relapsed or refractory multiple myeloma (rrmm)
- • Phase3 - 440 participants
- • The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with relapsed or refractory multiple myeloma (rrmm)
Where?
- • Cambridge - Addenbrooke's Hospital
- • London - University College London Hospital
- • Oxford - Churchill Hospital
- • Manchester - The Christie NHS Foundation Trust
- • +2 more UK sites
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
Biomarkers mentioned
Treatment history
Treatments you must have had:
- ✓ relapsed or refractory multiple myeloma (RRMM)
- ✓ a documented diagnosis of MM as per International Myeloma Working Group Criteria
- ✓ measurable disease during screening
- ✓ adequate organ function
What the study is looking for
- ✓Inclusion Criteria
- ✓Participants must have relapsed or refractory multiple myeloma (RRMM).
- ✓Participants must have a documented diagnosis of MM as per International Myeloma Working Group Criteria.
- ✓Participants must have cancer that can be measured on scans during screening.
- ✓Participants must have healthy organ.
See the full criteria
Where Is This Study? (6 UK sites)
Addenbrooke's Hospital
Cambridge CB2 2QQ, United Kingdom
University College London Hospital
London NW1 2PG, United Kingdom
Churchill Hospital
Oxford OX3 7LE, United Kingdom
The Christie NHS Foundation Trust
Manchester M20 4BX, United Kingdom
Freeman Hospital
Newcastle upon Tyne NE7 7DN, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield S10 2JF, United Kingdom
How to Get in Touch
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
Sponsor contactCONTACT
First line of the email MUST contain NCT # and Site #.
Sponsor contactCONTACT
