At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- BFR 80 (device), BFR40 (device)
- How long the study runs
- Study runs about 20 months (dates as stated)
- About the drug or intervention
- BFR 80 — device: The intervention involves placing a pneumatic tourniquet system over the proximal thigh. · BFR40 — device: The intervention involves placing a pneumatic tourniquet system over the proximal thigh.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years to 55 Years
- Who
- All
- Number of participants
- 28
- Started
- 2024-10-28
- Last checked
- 2024-11
Plain English Summary
What is this study?
- • Testing a new treatment for pain
- • NA - 28 participants
- • Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes
Who can take part?
- • Ages 18 Years to 55 Years
- • Diagnosed with pain
Where?
- • Loughborough - Defence Medical Rehabilitation Centre, Stanford Hall
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes. There are few exercise rehabilitation interventions able to relieve pain, thereby reducing the number of military personnel fit for operations. Low load blood flow restriction (BFR) exercise has been shown to elicit an analgesic response and promote beneficial physiological changes in a variety of clinical populations. This two phase study, aims to: * Determine the most effective and feasible BFR resistance exercise protocol for reducing pain in UK military patients. * Determine the efficacy of an optimal BFR exercise protocol for reducing pain and improving rehabilitation outcomes in UK military patients. * Identify key physiological mechanisms underpinning any beneficial effect of BFR exercise on pain. Consequently, results from this study will have direct clinical application and will aid best practice guidelines for the management of pain across Defence Rehabilitation by influencing the future rehabilitation paradigm. The investigators believe the results and impact will be far reaching, providing invaluable insight and knowledge to the clinical and scientific community to not only those embedded within Defence Rehabilitation, but also those working in civilian sector organisations and professional sport also.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 55 Years
- Who can join: All genders
What the study is looking for
- ✓Serving UK military personnel,
- ✓Aged 18-55,
- ✓Has unilateral lower limb injury whereby pain is the primary limiting factor hindering progression, as diagnosed by...
- ✓Reduced occupational employability and function,
- ✓Scheduled to attend DMRC Stanford Hall for 3 week residential rehabilitation course.
Who cannot take part
- ✗MSK-Specific Exclusion Criteria
- ✗Any medical safety concern related to BFR\*
- ✗Non-musculoskeletal or serious pathological condition (i.e. Inflammatory arthropathy, infection or tumour)
- ✗Spinal or referred pain from non-local pain source
- ✗Any pre-diagnosed physical impairment or co-morbidities (including cardio-vascular disease) precluding the safe...
See the full criteria
Where Is This Study? (1 UK site)
Defence Medical Rehabilitation Centre, Stanford Hall
Loughborough LE12 5QW, United Kingdom
How to Get in Touch
Peter Ladlow, PhD
Sponsor contactCONTACT
Luke Hughes, PhD
Sponsor contactCONTACT
