At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Not specified by the sponsor
- How long the study runs
- Study runs about 22 months (dates as stated)
- About the drug or intervention
- Not specified by the sponsor
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 25 Years to 60 Years
- Who
- All
- Number of participants
- 574
- Started
- 2024-09-02
- Last checked
- 2026-07
Plain English Summary
What is this study?
- • Testing a new treatment for huntington disease
- • Clinical study - 574 participants
- • For participation in this epidemiological study, a single-day visit at the study site is required
Who can take part?
- • Ages 25 Years to 60 Years
- • Diagnosed with huntington disease
Where?
- • Birmingham - Birmingham and Solihull Mental Health Foundation NHS Trust
- • Cambridge - Addenbrookes Hospital
- • London - National Hospital For Neurology and Neurosurgery
- • Oxford - John Radcliffe Hospital
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer questions regarding their demographics, including sex, age, race and ethnicity, and their medical and medication history. At the end of the visit, a blood sample will be drawn to allow testing with a sequencing assay that is specifically designed for phasing single nucleotide polymorphisms (SNPs) on the wild-type Huntington (wtHTT) and mutant Huntington (mHTT) alleles.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 25 Years - 60 Years
- Who can join: All genders
What the study is looking for
- ✓Have signed the agreement to take part Form (ICF)
- ✓Aged 25 to 60 years, inclusive, at the time of signing the ICF
- ✓Confirmation of Huntington Disease (HD) gene expansion mutation carrier status
- ✓Confirmation of Total Functional Capacity (TFC) ≥9 and Total Motor Score (TMS) \>6 within 12 months prior to signing...
- ✓Ability to tolerate blood draws
See the full criteria
Where Is This Study? (4 UK sites)
Birmingham and Solihull Mental Health Foundation NHS Trust
Birmingham B16 8PF, United Kingdom
Research & Development Department
bsmhft.researchanddevelopment@nhs.net0121-301 4343Addenbrookes Hospital
Cambridge CB2 0QQ, United Kingdom
National Hospital For Neurology and Neurosurgery
London WC1N 3BG, United Kingdom
John Radcliffe Hospital
Oxford OX3 9DU, United Kingdom