How do I find clinical trials in the UK?

Use TrialConnect to search by condition, location, or eligibility. We index over 29,000 UK clinical trials from ClinicalTrials.gov, updated daily. Enter your condition and we show matching trials near you.

Are there paid clinical trials in the UK?

Yes. Healthy volunteers can earn £500–£3,000 for Phase 1 and bioequivalence studies. TrialConnect lists paid research studies at UK research units in London, Leeds, Nottingham, and more.

What conditions have clinical trials available?

TrialConnect covers 41 conditions including breast cancer, lung cancer, diabetes, heart failure, COPD, multiple sclerosis, Parkinson's disease, Crohn's disease, and many more.

Is TrialConnect free?

Yes. TrialConnect is completely free for patients. We are not affiliated with the NHS or NIHR. Data is sourced from ClinicalTrials.gov.

Am I eligible for a clinical trial?

Each trial has specific eligibility criteria including age, condition, medical history, and current treatments. TrialConnect shows you trials that may match your situation, but only the trial team can confirm eligibility.

Endometrioma Sclerotherapy and Ovarian Preservation

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Access to the study treatment being tested
Type of study: Interventional (receives a drug or procedure)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Sclerotherapy (procedure), Routine Care (procedure)
How long the study runs: Study runs about 34 months (dates as stated)
About the drug or intervention: Sclerotherapy — procedure: Laparoscopic ethanol sclerotherapy of endometrioma · Routine Care — procedure: Routine surgical management of endometrioma
Patient visit burden: Not specified by the sponsor

Type of study: Testing a treatment
Ages: 18 Years to 45 Years
Who: Female
Number of participants: 60
Started: 2025-02-21
Last checked: 2025-11

Plain English Summary

What is this study?

• Testing a new treatment for endometrioma
• NA - 60 participants
• A randomised controlled trial assessing ovarian reserve after laparoscopic ethanol sclerotherapy of ovarian endometrioma compared to standard treatment of surgical excision of endometrioma

Who can take part?

• Ages 18 Years to 45 Years
• Diagnosed with endometrioma
• Female only

Where?

• London - Chelsea and Westminster NHS Foundation Trust

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

A randomised controlled trial assessing ovarian reserve after laparoscopic ethanol sclerotherapy of ovarian endometrioma compared to standard treatment of surgical excision of endometrioma. Secondary outcomes will include endometrioma recurrence, symptomatology and inflammatory environment.

More detail

Participants with endometrioma(ta), identified on imaging, who are opting for surgical management of endometriosis will be randomly allocated to laparoscopic ethanol sclerotherapy of endometrioma or laparoscopic surgical excision of endometrioma(ta). Any concurrent endometriosis identified at surgery will be excised as per routine care. Ovarian reserve will be assessed by serum anti-Mullarian hormone (AMH) and antral follicle count (AFC), recurrence will me assessed by transvaginal ultrasound, symptomatology will be assessed by EHP-30 questionnaires and changes in inflammation assessed in serum and endometrial biopsy. Each participant will be followed up for a total of 24 months from surgery.

Endometrioma

How this trial compares with your answers

Answer 2 more questions to improve match

What we know so far

Condition· Matched your search

Age· Tell us your age for better matching

Gender· Tell us your sex for better matching

Still need:

• Tell us your age for better matching
• Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: 18 Years - 45 Years
Who can join: Female only

What the study is looking for

✓Female (XX genotype, assigned female at birth)
✓Age 18-40

Who cannot take part

✗Postmenopausal status
✗Suspicion of cancer
✗Unable to undergo TVUSS
✗Declines to take part in the study
✗Unable to understand verbal or written information in English

See the full criteria

Inclusion Criteria: * Female (XX genotype, assigned female at birth) * Age 18-40 * Finding of suspected uni- or bi-lateral ovarian endometrioma(ta) of ≥ 2cm on TVUSS and/or pelvic MRI scan (TVUSS, a uni- or multi-locular ovarian cystic lesion with low level echoes and diffuse homogeneous ground glass appearance; MRI any of, ovarian lesion hyperintense T1 without loss of signal on T1 fat-suppressed images, hypointense T2 exhibiting shading sign and/or T2 dark spot sign, variable restricted diffusion on DWI) * Appropriate to be listed for laparoscopic excision of endometrioma (Endometrioma ≥2cm, pain symptoms attributable to endometriosis where medical management is unsuccessful or unacceptable to the patient, to facilitate ART) Exclusion Criteria: * Postmenopausal status * Suspicion of malignancy * Unable to undergo TVUSS * Declines to take part in the study * Unable to understand verbal or written information in English * Lack of capacity to consent at the point of recruitment * Known safeguarding issues

Where Is This Study? (1 UK site)

Chelsea and Westminster NHS Foundation Trust

London SW10 9NH, United Kingdom

Recruiting

Site contact (verified)

Gulsah Cetinkaya020 3315 6646 gulsah.cetinkaya1@nhs.net

How to Get in Touch

Sarah Bennet, BSc MBBS MRCOG

Sponsor contact

CONTACT

07983980924 sarah.bennet25@imperial.ac.uk

Thomas Bainton, BM BCh MRCOG MA(Oxon)

Sponsor contact

CONTACT

tombainton@doctors.org.uk

Data sourced from ClinicalTrials.gov · Last verified: 2025-11