At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Icotrokinra (drug), Placebo (drug)
- How long the study runs
- Study runs about 45 months (dates as stated)
- About the drug or intervention
- Icotrokinra — drug: Icotrokinra will be administered. · Placebo — drug: Placebo will be administered.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 750
- Started
- 2025-01-09
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for arthritis, psoriatic
- • Phase3 - 750 participants
- • The purpose of this study is to evaluate the efficacy of icotrokinra (JNJ-77242113) compared to placebo in biologic-experienced and biologic-naive participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with arthritis, psoriatic
Where?
- • Barnet - Royal Free London NHS Foundation Trust
- • Basingstoke - Basingstoke And North Hampshire Hospital
- • Christchurch - University Hospitals Dorset NHS Foundation Trust
- • Edinburgh - Western General Hospital
- • +7 more UK sites
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The purpose of this study is to evaluate the efficacy of icotrokinra (JNJ-77242113) compared to placebo in biologic-experienced and biologic-naive participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
Biomarkers mentioned
What the study is looking for
- ✓Have a diagnosis of PsA for at least 3 months before the first administration of study intervention and meet...
- ✓Have active plaque psoriasis with at least one psoriatic plaque of \>= 2 cm diameter or nail changes consistent with...
Who cannot take part
- ✗Currently has a cancer or has a history of cancer within 5 years prior to screening
- ✗Has known allergies, hypersensitivity, or intolerance to icotrokinra or its excipients
- ✗Participants with fibromyalgia or osteoarthritis symptoms that, in the investigator's opinion, would have potential...
See the full criteria
Where Is This Study? (11 UK sites)
Royal Free London NHS Foundation Trust
Barnet EN5 3DJ, United Kingdom
Basingstoke And North Hampshire Hospital
Basingstoke RG24 9NA, United Kingdom
University Hospitals Dorset NHS Foundation Trust
Christchurch BH23 2JX, United Kingdom
Western General Hospital
Edinburgh EH4 2XU, United Kingdom
Glasgow Royal Infirmary
Glasgow G31 2ER, United Kingdom
Hereford County Hospital
Hereford HR1 2ER, United Kingdom
Forth Valley Royal Hospital
Larbert FK5 4WR, United Kingdom
Haywood Hospital
Staffordshire ST6 7AG, United Kingdom
Torbay Hospital-Devon
Torquay TQ2 7AA, United Kingdom
New Cross Hospital
Wolverhampton WV10 0QP, United Kingdom
Betsi Cadwaladr University Health Board BCUHB
Wrexham LL13 7TD, United Kingdom
How to Get in Touch
Study Contact
Sponsor contactCONTACT
