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Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement

Sponsor: University of Portsmouth

NCT ID: NCT06829433

View on ClinicalTrials.gov ↗

At a glance

What the study gets you
Health checks and monitoring — no treatment given
Type of study
Observational (no treatment given)
Time in hospital
In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention
No intervention (other)
How long the study runs
Study runs about 28 months (dates as stated)
About the drug or intervention
No intervention — other: Observational cross-sectional study
Patient visit burden
Not specified by the sponsor
Type of study
Observing health over time
Ages
40 Years to 85 Years
Who
All
Number of participants
36
Started
2024-05-07
Last checked
2025-02

Plain English Summary

What is this study?

  • • Testing a new treatment for knee osteoarthritis
  • • Clinical study - 36 participants
  • • This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals

Who can take part?

  • • Ages 40 Years to 85 Years
  • • Diagnosed with knee osteoarthritis

Where?

  • • Portsmouth - School of Psychology, Health and Sport Sciences, University of Portsmouth

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals.

More detail

People living with OA tend to be less physically active than those without the disease, which is often due to pain, stiffness and joint instability. This reduction in physical activity can lead to additional health problems down the line. When the disease becomes severe, joint replacement surgeries are sometimes performed to relieve pain and improve individuals' quality of life. However, despite reducing pain, there is little evidence to show that joint replacement surgeries encourage individuals to return to healthy physical activity levels. Reasons for the lack of change may include a failure to address unhealthy walking and movement patterns which could still be causing pain and instability and reduced physical fitness levels. By investigating these reasons, we hope that findings from this study will help to inform future interventions that improve clinical outcomes and quality of life for individuals with OA and post-joint replacement.

Knee OsteoarthritisTotal Knee Replacement

How this trial compares with your answers

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What we know so far

Condition· Matched your search
Age· Tell us your age for better matching
Gender· Tell us your sex for better matching

Still need:

  • • Tell us your age for better matching
  • • Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

  • Age: 40 Years - 85 Years
  • Who can join: All genders

Who cannot take part

  • ✗Unable to walk at 0.8 m/s, exclusion based on IMO screening, non-English speaking, lacking ability to consent.
See the full criteria
Inclusion Criteria: * Diagnosed symptomatic bilateral or unilateral knee osteoarthritis, self-reported ability to walk without an aid for 10 minutes and to ascend and descend stairs, no neurological conditions or other musculoskeletal pathology/injury which would impact walking gait. Exclusion Criteria: * Unable to walk at 0.8 m/s, exclusion based on IMO screening, non-English speaking, lacking ability to consent.

Where Is This Study? (1 UK site)

School of Psychology, Health and Sport Sciences, University of Portsmouth

Portsmouth PO1 2ER, United Kingdom

Recruiting
Site contact (verified)
Josie Morris, BScPrincipal Investigator

How to Get in Touch

Josie Morris, BSc

Sponsor contact

CONTACT

02392 846395 josie.morris@port.ac.uk

Joseph Moore, PhD

Sponsor contact

CONTACT

joseph.moore@port.ac.uk
Data sourced from ClinicalTrials.gov · Last verified: 2025-02