At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Ureteric stenting (procedure), Indocyanine green (ICG) dye (procedure)
- How long the study runs
- Study runs about 32 months (dates as stated)
- About the drug or intervention
- Ureteric stenting — procedure: The ICE trial is a pilot study involving two methods for identifying the ureters (tubes connecting the kidneys to the bladder) during endometriosis surgery. · Indocyanine green (ICG) dye — procedure: The ICE trial is a pilot study involving two methods for identifying the ureters (tubes connecting the kidneys to the bladder) during endometriosis surgery.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years to 50 Years
- Who
- Female
- Number of participants
- 70
- Started
- 2025-07-29
- Last checked
- 2025-08
Plain English Summary
What is this study?
- • Testing a new treatment for endometriosis
- • Clinical study - 70 participants
- • Endometriosis is a common (around 1 in 10 women), non-cancerous condition where tissue similar to the womb lining is found growing elsewhere, most commonly inside the pelvis
Who can take part?
- • Ages 18 Years to 50 Years
- • Diagnosed with endometriosis
- • Female only
Where?
- • Stoke-on-Trent - University Hospitals of North Midlands NHS Trust
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
Endometriosis is a common (around 1 in 10 women), non-cancerous condition where tissue similar to the womb lining is found growing elsewhere, most commonly inside the pelvis. Symptoms vary but can include intense pelvic pain and infertility. Endometriosis that is very deep and painful may need surgery, which risks damage to the tubes that drain urine from the kidneys to the bladder (ureters). To reduce this risk, surgeons may put tiny plastic tubes called "stents" inside the ureters. These stents can stay for up-to 4 weeks following surgery but can cause severe pain and blood in the urine. Squirting a dye into the ureters, rather than using stents, may cause less pain for women after surgery whilst not making the removal of endometriosis worse, the operation take longer, or increasing the rates of complications (such as bleeding or damage to internal organs). Before a full clinical study can be run, the investigators need to understand whether this is possible, by doing a feasibility study
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 50 Years
- Who can join: Female only
What the study is looking for
- ✓Women aged 18 to 50 years
- ✓Scheduled for laparoscopic or robotic-assisted surgical excision of deep endometriosis (DE) where ureteric stenting...
- ✓Willing and able to provide consent for participation in the study
Who cannot take part
- ✗Confirmed or suspected pregnancy at the time of enrolment.
- ✗Suspicion or confirmation of cancer.
- ✗History of ureteric injury from prior surgery or trauma
- ✗Medically unfit for surgery due to the following conditions:
- ✗Uncontrolled diabetes mellitus.
See the full criteria
Where Is This Study? (1 UK site)
University Hospitals of North Midlands NHS Trust
Stoke-on-Trent ST4 6QG, United Kingdom
How to Get in Touch
Aviva Ogbolosingha
Sponsor contactCONTACT