At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- GHZ339 (drug), Placebo (drug)
- How long the study runs
- Study runs about 43 months (dates as stated)
- About the drug or intervention
- GHZ339 — drug: GHZ339 administered at dose A, B, C and D · Placebo — drug: Matching placebo
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years to 100 Years
- Who
- All
- Number of participants
- 224
- Started
- 2025-05-16
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for atopic dermatitis
- • Phase2 - 224 participants
- • This trial is designed to evaluate multiple compounds in participants with moderate to severe atopic dermatitis (AD)
Who can take part?
- • Ages 18 Years to 100 Years
- • Diagnosed with atopic dermatitis
Where?
- • Dudley - Novartis Investigative Site
- • Liverpool - Novartis Investigative Site
- • London - Novartis Investigative Site
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
This trial is designed to evaluate multiple compounds in participants with moderate to severe atopic dermatitis (AD).
More detail
This is a multicenter, randomized, double-blind, placebo-controlled Phase II platform study to investigate the efficacy and safety of several interventions in participants with moderate to severe AD. The first intervention planned to be evaluated is GHZ339. Participants will be randomly assigned to one of the study arms.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 100 Years
- Who can join: All genders
Treatment history
Treatments you must have had:
- ✓ systemic corticosteroids (e
What the study is looking for
- ✓Key Inclusion Criteria of the master protocol:
- ✓Able and willing to sign the agreement to take part (IC)
- ✓Patients with a diagnosis of AD and onset of disease for at least 1 year
- ✓Moderate to severe AD
- ✓Key Exclusion Criteria of the master protocol:
See the full criteria
Where Is This Study? (3 UK sites)
Novartis Investigative Site
Dudley DY1 2HQ, United Kingdom
Novartis Investigative Site
Liverpool L7 8XP, United Kingdom
Novartis Investigative Site
London SE1 9RT, United Kingdom
How to Get in Touch
Novartis Pharmaceuticals
Sponsor contactCONTACT
Novartis Pharmaceuticals
Sponsor contactCONTACT
