At a glance
- What the study gets you
- Health checks and monitoring — no treatment given
- Type of study
- Observational (no treatment given)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- CT coronary angiography (diagnostic test)
- How long the study runs
- Study runs about 53 months (dates as stated)
- About the drug or intervention
- CT coronary angiography — diagnostic test: To assess the presence of obstructive coronary artery disease, participants will either have coronary angiography as part of their routine care or they will return for a research CT scan of their heart (CT Coronary Angiogram)
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Observing health over time
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 300
- Started
- 2025-05-01
- Last checked
- 2026-06
Plain English Summary
What is this study?
- • Testing a new treatment for atrial fibrillation (af)
- • Clinical study - 300 participants
- • The goal of this observational study is to better understand the role of measuring troponin (a protein measured by a blood test) and coronary imaging in patients presenting with rapid atrial fibrillation (AF) The main questions this study aims to answer are: 1
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with atrial fibrillation (af)
Where?
- • Edinburgh - Royal Infirmary of Edinburgh
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The goal of this observational study is to better understand the role of measuring troponin (a protein measured by a blood test) and coronary imaging in patients presenting with rapid atrial fibrillation (AF) The main questions this study aims to answer are: 1. Are patients with a fast, irregular heartbeat (rapid AF) and damage to the heart (myocardial injury) more likely than those without damage to the heart to have blocked heart arteries (obstructive coronary artery disease) 2. Are patients with a fast, irregular heartbeat (rapid AF) and damage to the heart (myocardial injury) with further evidence that their heart hasn't been getting enough oxygen (myocardial ischemia) more likely to have imaging evidence of myocardial infarction than those without myocardial ischemia To do this, we will measure troponin in patients with rapid AF and then carry out further investigations of the heart (electrocardiogram, echocardiogram, CT scan and cardiac MRI)
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
Biomarkers mentioned
What the study is looking for
- ✓Age 18 years and over
- ✓Primary presentation with symptoms related to atrial fibrillation
- ✓Atrial fibrillation with a ventricular rate \>100 bpm on a 12-lead electrocardiogram
- ✓Able to provide agreement to take part
- ✓Exclusion Criteria
See the full criteria
Where Is This Study? (1 UK site)
Royal Infirmary of Edinburgh
Edinburgh, United Kingdom