At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Imeroprubart (drug), Placebo (drug)
- How long the study runs
- Study runs about 62 months (dates as stated)
- About the drug or intervention
- Imeroprubart — drug: Dose 1 subcutaneous (SC) once weekly (QW) for 24 weeks (Period 1) and 52 weeks (Period 2) · Placebo — drug: Matching placebo SC QW for 24 weeks (Period 1)
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 162
- Started
- 2025-03-18
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for chronic inflammatory demyelinating polyneuropathy
- • Phase2 - 162 participants
- • This is a Phase 2b study to evaluate the efficacy and safety of Imeroprubart in adults with CIDP
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with chronic inflammatory demyelinating polyneuropathy
Where?
- • Bristol - Site Number - 7001
- • Glasgow - Site Number - 7002
- • Salford - Site Number - 7000
- • Southampton - Site Number - 7003
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
This is a Phase 2b study to evaluate the efficacy and safety of Imeroprubart in adults with CIDP.
More detail
This is a multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of Imeroprubart in adult participants with active CIDP.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
Biomarkers mentioned
What the study is looking for
- ✓Have electrodiagnostic test results supporting the diagnosis of CIDP per the EAN/PNS guideline on diagnosis and...
- ✓Additional inclusion criteria are defined in the protocol.
Who cannot take part
- ✗Have current or prior history of IgM paraproteinemia with or without anti-myelin-associated-glycoprotein antibodies.
- ✗Have distal, sensory, or focal CIDP, or have a diagnosis of autoimmune nodopathy per the EAN/PNS guideline on...
- ✗Have polyneuropathy of causes other than CIDP including but not limited to:
- ✗Multifocal motor neuropathy
- ✗Hereditary demyelinating neuropathy
See the full criteria
Where Is This Study? (4 UK sites)
Site Number - 7001
Bristol, United Kingdom
Site Number - 7002
Glasgow, United Kingdom
Site Number - 7000
Salford, United Kingdom
Site Number - 7003
Southampton, United Kingdom
How to Get in Touch
Study Contact
Sponsor contactCONTACT
