At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Sarmentosin - L- theanine (supplement), Resistance Training (other), Placebo Supplement (supplement)
- How long the study runs
- Study runs about 13 months (dates as stated)
- About the drug or intervention
- Sarmentosin - L- theanine — supplement: Two capsules to give an overall dose of 20 mg of Sarmentosin and 400mg of L-theanine · Resistance Training — other: Home-based Resistance training. · Placebo Supplement — supplement: Capsules matched for taste and appearance, without any active ingredients.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 40 Years to 55 Years
- Who
- Female
- Number of participants
- 72
- Started
- 2026-03-01
- Last checked
- 2026-03
Plain English Summary
What is this study?
- • Testing a new treatment for perimenopause
- • NA - 72 participants
- • The aim of this clinical trial is to determine if resistance training and a newly developed plant-based nutritional supplement can improve the symptoms and musculoskeletal health of perimenopausal women
Who can take part?
- • Ages 40 Years to 55 Years
- • Diagnosed with perimenopause
- • Female only
Where?
- • Leeds - Carnegie School of Sport
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The aim of this clinical trial is to determine if resistance training and a newly developed plant-based nutritional supplement can improve the symptoms and musculoskeletal health of perimenopausal women. The main questions it aims to evaluate are: 1. Can resistance training and the nutritional supplement - both independently and in combination - improve perimenopausal symptoms (e.g. cognition, mood, sleep) and musculoskeletal outcomes (e.g. strength, muscle mass)? 2. What are the acute effects of the nutritional supplement on cognitive function and mood in perimenopausal women, and is this response altered following long-term intake (12 weeks)? 3. What mechanisms may be contributing to the results? Participants will be split into four groups to allow the researchers to answer the above questions. These are: 1. The nutritional supplement + resistance training 2. The nutritional supplement only 3. The placebo supplement (A look alike capsule that contains no active ingredients) and resistance training 4. The Placebo supplement only. Participants will: * Take their allocated supplement daily and perform home-based strength exercise 3 times per week (for exercise groups), for 12 weeks. * Attend the laboratory at the beginning and end of the 12 weeks to assess cognitive function and mood following acute intake of the supplement. * Attend the laboratory every 4 weeks during the 12 week period, for assessment of cognitive function, symptom severity and muscle health. * Provide a blood sample at each visit for assessment of mechanistic pathways.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 40 Years - 55 Years
- Who can join: Female only
What the study is looking for
- ✓Inclusion criteria
- ✓Perimenopausal women between 40 - 55 years
- ✓Not currently engaging in consistent structured resistance training (defined as \>3 resistance training sessions per...
- ✓Not on any HRT or hormonal contraception for at least one year before initiation of the study.
- ✓Able to attend laboratory visits and commit to the intervention schedule for 6 months.
See the full criteria
Where Is This Study? (1 UK site)
Carnegie School of Sport
Leeds LS2 3AE, United Kingdom
How to Get in Touch
Harriet Cannell
Sponsor contactCONTACT
Theocharis Ispogolou
Sponsor contactCONTACT
