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Treatment Effectiveness in People With axSpA or PsA Starting Treatment With Bimekizumab, Risankizumab, Guselkumab, Upadacitinib, or a TNF Inhibitor

Sponsor: Adelphi Real World

NCT ID: NCT07166315

View on ClinicalTrials.gov ↗

At a glance

What the study gets you
Health checks and monitoring — no treatment given
Type of study
Observational (no treatment given)
Time in hospital
In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention
observational study (other)
How long the study runs
Study runs about 20 months (dates as stated)
About the drug or intervention
observational study — other: This is an observational study based on existing treatments prescribed prior to inclusion.
Patient visit burden
Not specified by the sponsor
Type of study
Observing health over time
Ages
18 Years and over
Who
All
Number of participants
700
Started
2025-07-07
Last checked
2025-09

Plain English Summary

What is this study?

  • • Testing a new treatment for axial spondylarthritis (axspa)
  • • Clinical study - 700 participants
  • • This observational study will target patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) who have started treatment with bimekizumab, upadacitinib, risankizumab, guselkumab, or a tumour necrosis factor-alpha inhibitor (e

Who can take part?

  • • Ages 18 Years and over
  • • Diagnosed with axial spondylarthritis (axspa)

Where?

  • • Bath - Royal National Hospital for Rheumatic Diseases

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

This observational study will target patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) who have started treatment with bimekizumab, upadacitinib, risankizumab, guselkumab, or a tumour necrosis factor-alpha inhibitor (e.g., adalimumab or etanercept) at NHS hospitals in the United Kingdom. Information from patients' medical records will be collected, and patients will complete surveys about their experiences with their treatment. The study will look at treatment effectiveness from both healthcare professionals' and patients' points of view.

More detail

Patient experience surveys will be administered prospectively throughout the study period, whereas the review of patients' medical records will be conducted retrospectively towards the end of the study period.

Axial Spondylarthritis (axSpA)Psoriatic Arthritis (PsA)

How this trial compares with your answers

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What we know so far

Condition· Matched your search
Age· Tell us your age for better matching
Gender· Tell us your sex for better matching

Still need:

  • • Tell us your age for better matching
  • • Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

  • Age: 18 Years and over
  • Who can join: All genders

Biomarkers mentioned

PsA

What the study is looking for

  • ✓Participant has a clinical diagnosis of axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA).
  • ✓Participant has been prescribed advanced therapy within one month prior to enrolment in the study, to treat their...
  • ✓Participant is aged 18 years or older at enrolment.

Who cannot take part

  • ✗Participation in a clinical trial at enrolment.
See the full criteria
Inclusion Criteria: * Participant has a clinical diagnosis of axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA). * Participant has been prescribed advanced therapy within one month prior to enrolment in the study, to treat their axSpA or PsA. * Participant is aged 18 years or older at enrolment. Exclusion Criteria: -Participation in a clinical trial at enrolment.

Where Is This Study? (1 UK site)

Royal National Hospital for Rheumatic Diseases

Bath BA1 3NG, United Kingdom

Recruiting
Site contact (verified)
Dr William TillettPrincipal Investigator

How to Get in Touch

SpA Extend Team

Sponsor contact

CONTACT

+441625 577 829 arwspaextend@adelphigroup.com
Data sourced from ClinicalTrials.gov · Last verified: 2025-09