At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- AZD6234 Formulation 1 (drug), AZD6234 Formulation 2 (low concentration) (drug), AZD6234 Formulation 2 (high concentration) (drug), AZD6234 Formulation 3 (drug)
- How long the study runs
- Study runs about 18 months (dates as stated)
- About the drug or intervention
- AZD6234 Formulation 1 — drug: AZD6234 Formulation 1 will be administered as a single SC injection · AZD6234 Formulation 2 (low concentration) — drug: AZD6234 Formulation 2 (low concentration) will be administered as a single SC injection · AZD6234 Formulation 2 (high concentration) — drug: AZD6234 Formulation 2 (high concentration) will be administered as a single SC injection · AZD6234 Formulation 3 — drug: AZD6234 Formulation 3 will be administered as a single SC injection
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years to 55 Years
- Who
- All
- Number of participants
- 19
- Started
- 2025-11-11
- Last checked
- 2026-08
Plain English Summary
What is this study?
- • Testing a new treatment for healthy participants
- • Phase1 - 19 participants
- • This study in healthy volunteers aims to compare blood levels and side effects after administration of different formulations of AZD6234
Who can take part?
- • Ages 18 Years to 55 Years
- • Diagnosed with healthy participants
Where?
- • Ruddington - Research Site
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
This study in healthy volunteers aims to compare blood levels and side effects after administration of different formulations of AZD6234. This study will take place at one site in Nottingham, United Kingdom, and will enrol 21 healthy men and women aged 18-55 years.
More detail
This study in healthy volunteers aims to compare blood levels and side effects after administration of different formulations of AZD6234. This study will take place at one site in Nottingham, United Kingdom. It plans to enrol 21 healthy men and women aged 18-55 years. Each volunteer will take part in 4 treatment periods and receive different formulations of AZD6234, by injection under the skin into the abdomen (stomach). In each period they'll be given a single dose without food. They'll stay in the clinic for 6 nights on 4 occasions, attend up to 10 outpatient visits, and take up to 19 weeks to finish the study. Blood and urine samples will be collected to: measure the amount of AZD6234 and its breakdown products, do safety tests and assess the effect of the test medicine on the immune system response.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 55 Years
- Who can join: All genders
What the study is looking for
- ✓Healthy males or non-pregnant, non-lactating females aged 18 to 55 years inclusive
- ✓BMI of 25.0 to 35.0 kg/m2 inclusive and weight ≥50 kg
Who cannot take part
- ✗History of any clinically important disease or disorder
- ✗Any clinically significant illness, medical/surgical procedure, or trauma within 4 weeks of the planned first dosing day
- ✗Clinically significant abnormal clinical chemistry, haematology, coagulation or urinalysis
- ✗Any clinically significant abnormal findings in vital signs
- ✗Any clinically significant abnormalities on 12-lead ECG
See the full criteria
Where Is This Study? (1 UK site)
Research Site
Ruddington NG11 6JS, United Kingdom