At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Tirzepatide (drug), Standard of Care (other)
- How long the study runs
- Study runs about 80 months (dates as stated)
- About the drug or intervention
- Tirzepatide — drug: Administered SC · Standard of Care — other: Standard of care
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 3,000
- Started
- 2025-11-24
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for obesity
- • Phase4 - 3,000 participants
- • The purpose of this study is to evaluate tirzepatide within a real-world setting to assess body weight loss and incidence of type 2 diabetes in adults without diabetes who have obesity and at least one weight-related comorbid condition
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with obesity
Where?
- • Altrincham - P91604 St John's Medical Centre
- • Ashton-under-Lyne - P89008 Ashton Medical Group
- • Bolton - Y02319 SSP Bolton General Practice
- • Bury - P83012 Tower Family Healthcare
- • +26 more UK sites
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The purpose of this study is to evaluate tirzepatide within a real-world setting to assess body weight loss and incidence of type 2 diabetes in adults without diabetes who have obesity and at least one weight-related comorbid condition. Eligible participants must be registered patients at a participating site. Participation in the study will last about 260 weeks.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
What the study is looking for
- ✓Have a body mass index ≥30 and ≤34.9 kilogram per square meter (kg/m2)
- ✓Have an increased waist to height ratio (defined by \>0.5)
- ✓Have at least one weight related comorbid condition
- ✓Have had at least one attempt to lose weight with lifestyle intervention (diet and physical activity)
Who cannot take part
- ✗Have type 1 diabetes, type 2 diabetes, or any other types of diabetes
- ✗Have had a change in body weight of greater than 5 kilograms (11 pounds) within 90 days prior to screening
See the full criteria
Where Is This Study? (30 UK sites)
P91604 St John's Medical Centre
Altrincham WA14 1PF, United Kingdom
P89008 Ashton Medical Group
Ashton-under-Lyne OL6 6EW, United Kingdom
Y02319 SSP Bolton General Practice
Bolton BL1 4TH, United Kingdom
Alison Loftus. R&D Co-ordinator
alison.loftus@boltonft.nhs.uk01204 390390 ext. 3848P83012 Tower Family Healthcare
Bury BL9 0NJ, United Kingdom
P91014 Washway Road Medical Centre
Cheshire M33 7SS, United Kingdom
P88007 Cheadle Hulme Medical Group (was Cheadle Hulme Health Centre) (Bridge House)
Cheshire SK8 5LL, United Kingdom
Y02790 SSP Bolton Medical Centre
Great Lever BL3 6PY, United Kingdom
Alison Loftus. R&D Co-ordinator
alison.loftus@boltonft.nhs.uk01204 390390 ext. 3848P89002 The Brooke Surgery
Hyde SK14 SK14 1AT, United Kingdom
P84035 Bodey Medical Centre
Manchester M14 6WP, United Kingdom
P84630 The Arch Medical Practice
Manchester M15 5TJ, United Kingdom
P84678 Didsbury Medical Centre
Manchester M20 2ER, United Kingdom
P84017 Ladybarn Group Practice
Manchester M20 4SS, United Kingdom
P84068 Chorlton Family Practice
Manchester M21 9NJ, United Kingdom
P84012 Northenden Group Practice
Manchester M22 4DH, United Kingdom
P86004 Peterloo Medical Centre
Manchester M24 4DZ, United Kingdom
P83025 St Gabriels Medical Centre
Manchester M25 0HT, United Kingdom
P87019 Silverdale Medical Practice
Manchester M27 8 HP, United Kingdom
P91006 Urmston Group Practice
Manchester M41 8AA, United Kingdom
P92620 SSP Ince Surgery (Lower Ince)
Manchester WN3 4NW, United Kingdom
P84034 Barlow Medical Centre
Manchester, United Kingdom
P85010 Woodlands Medical Practice
Oldham OL9 0LH, United Kingdom
P85011 CH Medical Practice
Oldham OL9 8NH, United Kingdom
P86022 Stonefield Street Surgery
Rochdale OL16 4JF, United Kingdom
P91021 Firsway Health Centre
Sale M33 4BR, United Kingdom
P91013 Boundary House Medical Centre
Sale, United Kingdom
P87027 Langworthy Medical Practice
Salford M6 5WW, United Kingdom
P88632 Stockport Medical Group
Stockport SK3 9NX, United Kingdom
Research, Development & Innovation Office
research.development@stockport.nhs.uk0161 419 5893P87016 The Sides Medical Centre
Swinton M27 0EW, United Kingdom
P87025 The Lakes Medical Practice
Swinton M27 4AF, United Kingdom
Y02322 SSP Leigh Family Practice
Wigen WN7 2PE, United Kingdom
How to Get in Touch
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
Sponsor contactCONTACT
Physicians interested in becoming principal investigators please contact
Sponsor contactCONTACT