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Time-restricted Eating (TRE) and Protein in Older Adults

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Access to the study treatment being tested
Type of study: Interventional (receives a drug or procedure)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: TRE (other), ProtAM TRE (other), ProtPM TRE (other)
How long the study runs: Study runs about 19 months (dates as stated)
About the drug or intervention: TRE — other: * Participants will be asked to follow a 16:8 TRE protocol, consuming all their daily within 8 hours, between 12 and 8pm, and fast for 16 hours overnight. · ProtAM TRE — other: * Participants will be asked to follow a 16:8 TRE protocol, consuming all their daily within 8 hours, between 12 and 8pm, and fast for 16 hours overnight. · ProtPM TRE — other: * Participants will be asked to follow a 16:8 TRE protocol, consuming all their daily within 8 hours, between 12 and 8pm, and fast for 16 hours overnight.
Patient visit burden: Not specified by the sponsor

Type of study: Testing a treatment
Ages: 60 Years and over
Who: All
Number of participants: 80
Started: 2025-12
Last checked: 2025-11

Plain English Summary

What is this study?

• Testing a new treatment for generally healthy adults over 60 years old
• NA - 80 participants
• The aim this study is to investigate the effects of time-restricted eating (TRE) on body composition, muscle function and markers of metabolic health of adults over 60 years old

Who can take part?

• Ages 60 Years and over
• Diagnosed with generally healthy adults over 60 years old

Where?

• Guildford - University of Surrey

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

The aim this study is to investigate the effects of time-restricted eating (TRE) on body composition, muscle function and markers of metabolic health of adults over 60 years old. This study will compare different variations of TRE - with and without an additional protein. This study involves attending two study days at the University of Surrey for baseline and end-of-intervention measurement of body composition using a gold-standard dual energy x-ray absorptiometry (DEXA) scan; muscle function using hand grip strength and 30-second sit-to-stand tests; weight. A blood sample will be taken at each study visit to measure markers of lipid and glucose control, and insulin sensitivity. Participants will be randomly allocated to one of four study groups: * control group: maintain habitual dietary patterns * TRE group: fast for 16 hours overnight, eat between 12-8pm * TRE + Protein (AM): fast for 16 hours overnight, eat between 12-8pm; take a 30g plant-based protein supplement in the morning * TRE + Protein (PM): fast for 16 hours overnight, eat between 12-8pm; take a 30g plant-based protein supplement in the afternoon Participants will be asked to follow the intervention according to their allocated group for 8 weeks.

Generally Healthy Adults Over 60 Years Old

How this trial compares with your answers

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What we know so far

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: 60 Years and over
Who can join: All genders

What the study is looking for

✓Gender: male and female
✓Age range: 60 years or older
✓Fasting for 12 or less hours on a daily basis
✓BMI range: 23-30 kg/m2
✓Weight stability: no more than 3kg weight gain or loss in the past 3 months

Who cannot take part

✗Any of the following present (in line with exclusion criteria used in previous TRE research in older adults):
✗known kidney impairment
✗heart attack or stroke in the past three months
✗continuous use of supplemental oxygen to manage a chronic lung condition or heart failure
✗rheumatoid arthritis

See the full criteria

Inclusion Criteria: * Gender: male and female * Age range: 60 years or older * Fasting for 12 or less hours on a daily basis * BMI range: 23-30 kg/m2 * Weight stability: no more than 3kg weight gain or loss in the past 3 months * Regular eating pattern, i.e. 3 meals a day * Able to prepare the protein supplement Exclusion Criteria: * Any of the following present (in line with exclusion criteria used in previous TRE research in older adults): * known renal impairment * heart attack or stroke in the past three months * continuous use of supplemental oxygen to manage a chronic pulmonary condition or heart failure * rheumatoid arthritis * Parkinson's disease * active treatment for cancer in the past year * insulin dependent diabetes mellitus * taking medications that preclude fasting for 16 h * actively trying or planning to lose weight * history of an eating disorder * outside of stated age or BMI range * fasting for longer than 12 hours on a daily basis * unable to prepare the protein supplement * extreme morning/evening chronotype * sleep disorders * regular meal skipping * history of difficulty having a blood sample taken * Recent exposure to high-dose radiation * Vigorous exercise on more than 3 occasions a week

Where Is This Study? (1 UK site)

University of Surrey

Guildford GU2 7XH, United Kingdom

Recruiting

Site contact (verified)

Dr CollinsPrincipal Investigator

Yana Petkova+44 7513 679 635 yp00228@surrey.ac.uk

Dr Collinsa.collins@surrey.ac.uk

How to Get in Touch

Yana Petkova

Sponsor contact

CONTACT

+44 7513 679 635 yp00228@surrey.ac.uk

Dr Collins

Sponsor contact

CONTACT

a.collins@surrey.ac.uk

Data sourced from ClinicalTrials.gov · Last verified: 2025-11