At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- Eloralintide (drug), Placebo (drug)
- How long the study runs
- Study runs about 53 months (dates as stated)
- About the drug or intervention
- Eloralintide — drug: Administered SC · Placebo — drug: Administered SC
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years and over
- Who
- All
- Number of participants
- 1,980
- Started
- 2026-02-06
- Last checked
- 2026-09
Plain English Summary
What is this study?
- • Testing a new treatment for obesity
- • Phase3 - 1,980 participants
- • The purpose of this study is to evaluate the efficacy and safety of eloralintide in adults with obesity or overweight who do not have type 2 diabetes
Who can take part?
- • Ages 18 Years and over
- • Diagnosed with obesity
Where?
- • Blackpool - Layton Medical Centre
- • Bradford on Avon - Bradford on Avon Health Centre
- • Lancashire - Ashton Medical Group - Chapel House
- • Lancaster - Royal Lancaster Infirmary
- • +5 more UK sites
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The purpose of this study is to evaluate the efficacy and safety of eloralintide in adults with obesity or overweight who do not have type 2 diabetes. The study has two phases: a main phase and an extension phase. Participation in the main phase of the study will last about 75 weeks. Participants with prediabetes will continue in the extension phase for another 2 years.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years and over
- Who can join: All genders
What the study is looking for
- ✓Have Body Mass Index (BMI) at screening of the following:
- ✓30 kilogram per square meter (kg/m2) OR
- ✓27 kg/m2 with at least one of the following weight-related health conditions at screening:
- ✓high blood pressure
- ✓dyslipidemia
Who cannot take part
- ✗Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if...
- ✗Have a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy...
- ✗Have type 1 diabetes or type 2 diabetes
- ✗Have had within 90 days prior to screening:
- ✗heart attack
See the full criteria
Where Is This Study? (9 UK sites)
Layton Medical Centre
Blackpool FY3 7EN, United Kingdom
Bradford on Avon Health Centre
Bradford on Avon BA15 1DQ, United Kingdom
Ashton Medical Group - Chapel House
Lancashire OL6 6EW, United Kingdom
Royal Lancaster Infirmary
Lancaster LA1 4RP, United Kingdom
Altnagelvin Area Hospital
Londonderry BT47 6SB, United Kingdom
Bodyline Clinic - Openshaw
Manchester M11 1AA, United Kingdom
Wansford Research Limited
Peterborough PE8 6PL, United Kingdom
Abbeywell Surgery
Romsey SO51 7QN, United Kingdom
Rame Group Practice
Torpoint PL11 2TB, United Kingdom
How to Get in Touch
Trial question or participation questions: 1-877-CTLILLY (1-877-285-4559) or
Sponsor contactCONTACT
Physicians interested in becoming principal investigators please contact
Sponsor contactCONTACT
