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The Effectiveness of a Herbal Supplement in Osteoarthritis.

Sponsor: Middlesex University

NCT ID: NCT07324746

View on ClinicalTrials.gov ↗

At a glance

What the study gets you
Access to the study treatment being tested
Type of study
Interventional (receives a drug or procedure)
Time in hospital
In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention
Active treatment (supplement), Placebo (other)
How long the study runs
Study runs about 9 months (dates as stated)
About the drug or intervention
Active treatment — supplement: A dietary supplement containing standardised herbal extracts of Boswellia serrata (525 mg), Curcuma longa (150 mg), Vitis vinifera (75 mg). · Placebo — other: A placebo containing no standardised herbal extracts or other active ingredients.
Patient visit burden
Not specified by the sponsor
Type of study
Testing a treatment
Ages
18 Years and over
Who
All
Number of participants
30
Started
2025-12-05
Last checked
2025-06

Plain English Summary

What is this study?

  • • Testing a new treatment for osteoarthritis (oa)
  • • NA - 30 participants
  • • This study aims to evaluate the effectiveness and safety of a combined herbal supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera in adults with clinically diagnosed knee or hip osteoarthritis

Who can take part?

  • • Ages 18 Years and over
  • • Diagnosed with osteoarthritis (oa)

Where?

  • • London - Middlesex Univeristy London

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

This study aims to evaluate the effectiveness and safety of a combined herbal supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera in adults with clinically diagnosed knee or hip osteoarthritis. The primary objective is to determine whether the supplement improves osteoarthritis-related symptoms. The supplement will be compared with a placebo. Participants will: * take the supplement and placebo for 4 weeks each, one at a time; * complete validated questionnaires (6 times online) * perform three performance-based physical tests (6 times online) * provide a urine sample

Osteoarthritis (OA)Osteoarthritis (OA) of the HipOsteoarthritis (OA) of the KneeOsteoarthritis

How this trial compares with your answers

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What we know so far

Condition· Matched your search
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Still need:

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

  • Age: 18 Years and over
  • Who can join: All genders

What the study is looking for

  • ✓Aged ≥ 18
  • ✓Diagnosis of osteoarthritis in knee or hip
  • ✓Numerical Rating Scale (NRS) ≥ 4 during the most painful movement in the last 24 hours
  • ✓Lequesne's Functional Index (LFI) score ≥ 7
  • ✓Ambulant patient

Who cannot take part

  • ✗Pregnant and breastfeeding
  • ✗Autoimmune disease such as rheumatoid arthritis, gout, lupus
  • ✗Joint trauma, joint injury, joint infection, meniscus tear, complete loss of articular cartilage
  • ✗Expectation of surgery
  • ✗History of the viscous or corticosteroids injections into affected joints or oral corticosteroids within last 12 months
See the full criteria
Inclusion Criteria: * Aged ≥ 18 * Diagnosis of osteoarthritis in knee or hip * Numerical Rating Scale (NRS) ≥ 4 during the most painful movement in the last 24 hours * Lequesne's Functional Index (LFI) score ≥ 7 * Ambulant patient Exclusion Criteria: * Pregnant and breastfeeding * Autoimmune disease such as rheumatoid arthritis, gout, lupus * Joint trauma, joint injury, joint infection, meniscus tear, complete loss of articular cartilage * Expectation of surgery * History of the viscous or corticosteroids injections into affected joints or oral corticosteroids within last 12 months * Allergy to one of the intervention's ingredients or NSAIDs * Peptic ulceration and upper gastrointestinal haemorrhage * High alcohol intake, inability to abstain from alcohol, substance abuse, history of addiction * Tumor, cancer * Abnormal renal or/and hepatic functions or altered blood chemistry * Use of concomitant medication able to interfere with the interventions

Where Is This Study? (1 UK site)

Middlesex Univeristy London

London NW4 4BT, United Kingdom

Recruiting
Site contact (verified)
Patrycja Brodka Pedro, MScPrincipal Investigator
Patrycja Brodka Pedro, MScp.x.brodkapedro@mdx.ac.uk
Lygeri Dimitriou, Drl.dimitriou@mdx.ac.uk

How to Get in Touch

Patrycja Brodka Pedrp, MSc

Sponsor contact

CONTACT

020-8411-2721 p.x.brodkapedro@mdx.ac.uk

Lygeri Dimitriou, Dr

Sponsor contact

CONTACT

020-8411-4354 l.dimitriou@mdx.ac.uk
Data sourced from ClinicalTrials.gov · Last verified: 2025-06