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Exercising in Hot Conditions: How Does it Effect Blood Glucose in People With T1D

View on ClinicalTrials.gov ↗

At a glance

What the study gets you: Access to the study treatment being tested
Type of study: Interventional (receives a drug or procedure)
Time in hospital: In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention: Exercise (behavioural)
How long the study runs: Study runs about 12 months (dates as stated)
About the drug or intervention: Exercise — behavioural: exercise in the heat or temperate conditions
Patient visit burden: Not specified by the sponsor

Type of study: Testing a treatment
Ages: 18 Years to 65 Years
Who: All
Number of participants: 38
Started: 2025-11-01
Last checked: 2025-11

Plain English Summary

What is this study?

• Testing a new treatment for type 1 diabetes (t1d)
• NA - 38 participants
• A randomised, crossover, counterbalanced repeated measures study will be conducted to examine the effect of acute heat exposure on rate of change in blood glucose concentration during 40 minutes of moderate-intensity exercise and for 30 minutes after exercise

Who can take part?

• Ages 18 Years to 65 Years
• Diagnosed with type 1 diabetes (t1d)

Where?

• Liverpool - Liverpool John Moores University

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

A randomised, crossover, counterbalanced repeated measures study will be conducted to examine the effect of acute heat exposure on rate of change in blood glucose concentration during 40 minutes of moderate-intensity exercise and for 30 minutes after exercise. Participants will complete two experimental conditions during two separate laboratory visits, with the order of conditions randomised. One condition will be a temperate condition of 20°C with 50% relative humidity (Temperate), the other will be 40°C with 50% relative humidity (Heat). Visits will be identical, including time of day, except for the condition. Visits will be separated by 24h. Testing will take place in the laboratories of the Research Institute for Sport and Exercise Sciences at Liverpool John Moores University.

Type 1 Diabetes (T1D)

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What we know so far

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Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

Age: 18 Years - 65 Years
Who can join: All genders

What the study is looking for

✓T1D diagnosis more than 1 years ago (to ensure participants are out of the honeymoon period)
✓Using insulin therapy with multiple daily injections (MDI), insulin pump (pump), or hybrid closed-loop (HCL)
✓o If using a HCL system have experience of using a pre-programmed basal rate in manual mode during exercise
✓Aged 18-65 years
✓Regularly engaged in endurance exercise (training at least twice per week for ≥30 minutes per session)

Who cannot take part

✗Pregnancy
✗\<6 months postpartum or stopped breastfeeding \<1 month before recruitment
✗Existing cerebrovascular or cardiovascular disease
✗Significant history of hyperglycaemia (HbA1c \>85 mmol/mol)
✗History of severe hypoglycaemia requiring third party assistance within the last 3 months

See the full criteria

Inclusion Criteria: * T1D diagnosis more than 1 years ago (to ensure participants are out of the honeymoon period) * Using insulin therapy with multiple daily injections (MDI), insulin pump (pump), or hybrid closed-loop (HCL) o If using a HCL system have experience of using a pre-programmed basal rate in manual mode during exercise * Aged 18-65 years * Regularly engaged in endurance exercise (training at least twice per week for ≥30 minutes per session) Exclusion Criteria: * Pregnancy * \<6 months postpartum or stopped breastfeeding \<1 month before recruitment * Existing cerebrovascular or cardiovascular disease * Significant history of hyperglycaemia (HbA1c \>85 mmol/mol) * History of severe hypoglycaemia requiring third party assistance within the last 3 months * Body weight \<36.5kg * Difficulty swallowing tablets * Appointment for an MRI test that cannot be rescheduled * Obstructive gastrointestinal disease * History of gastrointestinal surgery * Have an implanted medical device

Where Is This Study? (1 UK site)

Liverpool John Moores University

Liverpool L33AF, United Kingdom

Recruiting

Site contact (verified)

Matthew Cocks, PhD4407540191292 m.s.cocks@ljmu.ac.uk

How to Get in Touch

Matthew Cocks, PhD

Sponsor contact

CONTACT

447540191292 m.s.cocks@ljmu.ac.uk

Data sourced from ClinicalTrials.gov · Last verified: 2025-11