At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- science lesson (behavioural), PE Lesson (behavioural)
- How long the study runs
- Study runs about 21 months (dates as stated)
- About the drug or intervention
- science lesson — behavioural: children have a 90 minute science lesson outdoors · PE Lesson — behavioural: CHildren have a 90 minute PE lesson outdoors
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 7 Years to 11 Years
- Who
- All
- Number of participants
- 330
- Started
- 2025-10-20
- Last checked
- 2026-06
Plain English Summary
What is this study?
- • Testing a new treatment for asthma acute
- • NA - 330 participants
- • The goal of this study is to see if physical activity in high air pollution is worse than rest in high air pollution
Who can take part?
- • Ages 7 Years to 11 Years
- • Diagnosed with asthma acute
Where?
- • London - Faculty of Medicine and Dentistry
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The goal of this study is to see if physical activity in high air pollution is worse than rest in high air pollution.
More detail
The study will recruit a total of 330 children from 10 primary schools split into two groups: "higher pollution" and "lower pollution" schools. The team shall invite children in years 3 to 6 to take part in the study and consent will be provided by parents following information sheets sent home in school bags and parent evening presentations. After the team have received written permission from parents. The study team will visit the school on two days. On the first day the study team will perform lung health assessment in a dedicated classroom. The assessment will involve, measuring children's height and weight, a breathing test (photo and a snot sample collected by squirting a small bit of saline water up one nostril and catching the snot in a cup. Children will then take part in a PE lesson or a sedentary science lesson in a random order in their school playground while wearing activity monitors - like a Fitbit- to track their physical activity. The session is designed to be just like a typical outdoor science or PE lesson and will be exactly the same at all schools. Air pollution levels in the playground will be monitored during this time. Once the PE lesson has finished the children will perform the same health assessment immediately after the lesson and again on a second day. The team shall compare the change in these scores between higher and lower pollution schools. The breathing tests will tell us if the has been any change in lung health and the snot samples will tell us about the pollution the children have breathed and how their bodies try to fight it. Participating will take about 4 hours total.
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 7 Years - 11 Years
- Who can join: All genders
What the study is looking for
- ✓Attending schools in Central and East London that have been recruited to the study
Who cannot take part
- ✗Not able to engage with PE lessons on safety grounds, reported by their parents.
- ✗Children with learning or physical disabilities sufficient for them to be unable to give informed assent to the...
See the full criteria
Where Is This Study? (1 UK site)
Faculty of Medicine and Dentistry
London E1 2AB, United Kingdom
How to Get in Touch
James Scales, PhD
Sponsor contactCONTACT
Abigail Whitehouse, MD,PhD
Sponsor contactCONTACT
