At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- urodynamic testing (diagnostic test), videourodynamic testing (diagnostic test)
- How long the study runs
- Study runs about 20 months (dates as stated)
- About the drug or intervention
- urodynamic testing — diagnostic test: The standard urodynamic studies (UDS, without X-rays) are performed in an outpatient setting by a doctor, clinical scientist or nurse. · videourodynamic testing — diagnostic test: Video-urodynamic studies (VUDS) can only be performed in a radiology department by a doctor, clinical scientist or nurse with specific X-ray training in the presence of a radiographer.
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 18 Years to 100 Years
- Who
- Female
- Number of participants
- 30
- Started
- 2025-10-06
- Last checked
- 2026-04
Plain English Summary
What is this study?
- • Testing a new treatment for stress incontinence female
- • NA - 30 participants
- • To asses feasibility of a prospective randomised trial comparing the outcomes of surgery for recurrent urinary incontinence after video-urodynamic(VCMG)and urodynamic(UDS)investigations
Who can take part?
- • Ages 18 Years to 100 Years
- • Diagnosed with stress incontinence female
- • Female only
Where?
- • London - University College Hospital at Westmoreland Street
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
To asses feasibility of a prospective randomised trial comparing the outcomes of surgery for recurrent urinary incontinence after video-urodynamic(VCMG)and urodynamic(UDS)investigations. One of the greatest challenges for clinicians is the lack of correlation between bothersome urinary symptoms and the underlying urinary tract dysfunction. This has led to the development of several investigations aimed at improving diagnostic accuracy, with UDS and VUDS being the most noteworthy. Despite the heavy reliance on these invasive tests by clinicians, their indications and efficacy remain controversial and supporting literature data is scarce and nonvalidated. The investigators will perform a prospective randomised study of 30 women referred to our tertiary urological services at University College London Hospitals (UCLH) for treatment of recurrent stress urinary incontinence. The women will be investigated with either UDS or VUDS prior to receiving medical and surgical treatment tailored to the identified underlying urinary tract dysfunction. Adult women with symptoms suggestive of recurrent stress urinary incontinence after failed continence surgery will be included. Women who are pregnant, unfit for surgery, have a background of pelvic radiotherapy or relevant neurogenic disease that would put them at risk of neurogenic bladder will be excluded. UDS/VUDS will be performed under the care of Functional, Reconstructive and Adolescent Urology (FFA) Urology Service at UCLH adhering to standardised protocols. Treatment will be provided by FRA Team at UCLH. The primary outcome is assessment of symptoms of urinary incontinence by using validated questionnaires. Results will be correlated with patient characteristics, X-ray exposure, patient experience metrics, outcome and expenses to determine in which sub-populations performing UDS or VUDS has a higher impact on outcomes and when they should be avoided.
How this trial compares with your answers
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What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 18 Years - 100 Years
- Who can join: Female only
What the study is looking for
- ✓competent (able to consent)
- ✓adult women (over 18 years old)
- ✓with recurrent stress urinary incontinence
Who cannot take part
- ✗women who are pregnant
- ✗unfit for surgery
- ✗body mass index (BMI) over 35
- ✗background of pelvic radiotherapy or relevant neurogenic disease that would put them at risk of neurogenic bladder
See the full criteria
Where Is This Study? (1 UK site)
University College Hospital at Westmoreland Street
London W1G 8PH, United Kingdom
How to Get in Touch
Bogdan Toia, MD (Romania)
Sponsor contactCONTACT