Skip to main content
UK clinical trials - updated daily from ClinicalTrials.gov
TrialConnect
← Back to Search
Looking for participantsN/A

Mavacamten Outcomes in Hypertrophic Cardiomyopathy (HCM) and the Associated Patient and Physician Experiences in the US

Sponsor: Bristol-Myers Squibb

NCT ID: NCT07557498

View on ClinicalTrials.gov ↗

At a glance

What the study gets you
Health checks and monitoring — no treatment given
Type of study
Observational (no treatment given)
Time in hospital
In-person visits at study sites — visit count not specified by the sponsor
Drug or intervention
Mavacamten (drug)
How long the study runs
Study runs about 17 months (dates as stated)
About the drug or intervention
Mavacamten — drug: According to the product label
Patient visit burden
Not specified by the sponsor
Type of study
Observing health over time
Ages
18 Years and over
Who
All
Number of participants
362
Started
2026-01-15
Last checked
2026-04

Plain English Summary

What is this study?

  • • Testing a new treatment for obstructive hypertrophic cardiomyopathy (ohcm)
  • • Clinical study - 362 participants
  • • The purpose of this study is to understand the real-world clinical outcomes and treatment patterns of adults with obstructive hypertrophic cardiomyopathy (HCM) treated with mavacamten, and to understand patient and physician experiences with mavacamten treatment, in the US community-based practice

Who can take part?

  • • Ages 18 Years and over
  • • Diagnosed with obstructive hypertrophic cardiomyopathy (ohcm)

Where?

  • • Bollington - Adelphi Real World

This is a simplified summary. Always discuss with your doctor before making any decisions.

About This Trial

The purpose of this study is to understand the real-world clinical outcomes and treatment patterns of adults with obstructive hypertrophic cardiomyopathy (HCM) treated with mavacamten, and to understand patient and physician experiences with mavacamten treatment, in the US community-based practice

Obstructive Hypertrophic Cardiomyopathy (oHCM)

How this trial compares with your answers

Answer 2 more questions to improve match

What we know so far

Condition· Matched your search
Age· Tell us your age for better matching
Gender· Tell us your sex for better matching

Still need:

  • • Tell us your age for better matching
  • • Tell us your sex for better matching

Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.

Eligibility at a Glance

Key info

  • Age: 18 Years and over
  • Who can join: All genders

Biomarkers mentioned

met

What the study is looking for

  • ✓Phase I: retrospective chart review
  • ✓For inclusion in the study, participants must meet ALL of the following criteria:
  • ✓Are an adult aged 18 or over at baseline
  • ✓Have a confirmed diagnosis of obstructive hypertrophic cardiomyopathy (HCM)
  • ✓Have been prescribed mavacamten for obstructive HCM at one of the study sites between 28th April 2022 and 31st...

Who cannot take part

  • ✗None with the proviso that all inclusion criteria are met.
See the full criteria
Inclusion Criteria: Phase I: retrospective chart review For inclusion in the study, participants must meet ALL of the following criteria: * Are an adult aged 18 or over at baseline * Have a confirmed diagnosis of obstructive hypertrophic cardiomyopathy (HCM) * Have been prescribed mavacamten for obstructive HCM at one of the study sites between 28th April 2022 and 31st December 2024 * Have not ever been enrolled in any interventional clinical trial involving any cardiac myosin inhibitor (enrollment in observational studies is permitted) * Are not enrolled in any interventional clinical trial at study baseline Phase II: patient survey • Participants must meet all inclusion criteria of Phase I: retrospective chart review and be able to read and understand English and have access to computer or smartphone to complete the survey Exclusion Criteria: • None with the proviso that all inclusion criteria are met.

Where Is This Study? (1 UK site)

Adelphi Real World

Bollington SK10 5JB, United Kingdom

Recruiting
Site contact (verified)
USA Generic Country, Site 00010000000000

How to Get in Touch

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

Sponsor contact

CONTACT

855-907-3286 Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Sponsor contact

CONTACT

Data sourced from ClinicalTrials.gov · Last verified: 2026-04