At a glance
- What the study gets you
- Access to the study treatment being tested
- Type of study
- Interventional (receives a drug or procedure)
- Time in hospital
- In-person visits at study sites — visit count not specified by the sponsor
- Drug or intervention
- A diet containing plant foods (other), A diet containing different plant foods (other)
- How long the study runs
- Study runs about 31 months (dates as stated)
- About the drug or intervention
- A diet containing plant foods — other: Study meals, snacks and drinks will be provided that contain plant foods for four weeks (6 days a week). · A diet containing different plant foods — other: Study meals, snacks and drinks will be provided that contain plant foods for four weeks (6 days a week).
- Patient visit burden
- Not specified by the sponsor
- Type of study
- Testing a treatment
- Ages
- 30 Years to 70 Years
- Who
- All
- Number of participants
- 248
- Started
- 2026-04
- Last checked
- 2025-10
Plain English Summary
What is this study?
- • Testing a new treatment for healthy adult volunteers
- • NA - 248 participants
- • The aim of this randomised controlled trial is to investigate the effects of plant foods on gastrointestinal and cardiometabolic health in healthy adults aged 30-70 years old
Who can take part?
- • Ages 30 Years to 70 Years
- • Diagnosed with healthy adult volunteers
Where?
- • London - King's College London
This is a simplified summary. Always discuss with your doctor before making any decisions.
About This Trial
The aim of this randomised controlled trial is to investigate the effects of plant foods on gastrointestinal and cardiometabolic health in healthy adults aged 30-70 years old. The main question it will answer is "what is the effect of plant foods on alpha-diversity of the gut microbiota?". Researchers will compare two diets containing plant foods to see if they have different effects on gastrointestinal and cardiometabolic health. Participants will be asked to replace all their meals, snacks and drinks with those provided by the study team for four weeks (6 days/week). Participants will also be asked to attend the research facility on three occasions to: * Provide a blood sample * Provide a urine sample * Provide a stool sample * Have their body composition assessed * Have an ultrasound of their artery (arm) * Have their blood pressure measured * Answer questionnaires related to dietary intake, mental health, physical activity, quality of life, diet acceptability and adherence
How this trial compares with your answers
Answer 2 more questions to improve match
What we know so far
Still need:
- • Tell us your age for better matching
- • Tell us your sex for better matching
Preliminary match based on your answers. Full eligibility requires on-site assessment including medical history, physical exam, and lab tests. This does not guarantee enrolment.
Eligibility at a Glance
Key info
- Age: 30 Years - 70 Years
- Who can join: All genders
What the study is looking for
- ✓Adults aged 30-70 years of age
- ✓Capacity to give agreement to take part in English
- ✓Consume equal or less than the average UK plant food intake (number and quantity)
- ✓Consume less than 30 g/d of fibre
- ✓BMI 18.50-29.99 kg/m2
Who cannot take part
- ✗A current diagnosis of IBS, as defined by the Rome IV criteria.
- ✗Taking medications known to affect outcomes of interest, including:
- ✗Prebiotics and probiotics 4 weeks prior to enrolment.
- ✗Antibiotics within 4 weeks of enrolment.
- ✗Medications known to affect blood pressure, appetite, gut motility, glucose control, or lipid levels within 4 weeks...
See the full criteria
Where Is This Study? (1 UK site)
King's College London
London SE1 9NH, United Kingdom
